CDC42EP2 and COX5B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CDC42EP2	COX5B
Description		CDC42 effector protein 2	cytochrome c oxidase subunit 5B
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Endomembrane System Microtubule Cytoskeleton Membrane Phagocytic Vesicle	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex IV
	Molecular Function	Opioid Peptide Activity GTPase Activator Activity Protein Binding Small GTPase Binding	Cytochrome-c Oxidase Activity Protein Binding Metal Ion Binding
	Biological Process	Actin Filament Organization Rho Protein Signal Transduction Regulation Of Cell Shape Actin Cytoskeleton Organization Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Pseudopodium Assembly Positive Regulation Of Protein-containing Complex Assembly Regulation Of Catalytic Activity Cellular Response To Interferon-gamma	Mitochondrial Electron Transport, Cytochrome C To Oxygen Respiratory Gaseous Exchange By Respiratory System Proton Transmembrane Transport
Pathways		MAPK6/MAPK4 signaling CDC42 GTPase cycle RHOQ GTPase cycle	TP53 Regulates Metabolic Genes Respiratory electron transport Cytoprotection by HMOX1
Drugs			Cholic Acid N-Formylmethionine
Diseases
GWAS		Acne (severe) ( 24927181) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494 27863252)	Bipolar disorder ( 31043756) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		11 interacting genes: ARHGAP26 CASS4 CDC42 COX5B NEDD9 NME7 PICK1 RHOQ SEPTIN6 SEPTIN7 SNCA	36 interacting genes: AR ARID5A BHLHE40 CDC42EP2 CDR2 CDR2L DOK3 FAM228A FLOT1 GOLGA2 IHO1 KRT15 KRT27 KRT31 KRT33B LSM4 MCCD1 MID2 NPHP1 NUDT5 OIP5 PLEKHF2 PNMA1 PPP1R32 PRDM6 PRKAR1B PRR22 RBM48 SLAIN1 TASOR2 TEX12 TFIP11 TRAF1 TRIM23 TRIM27 VPS28
Entrez ID		10435	1329
HPRD ID		09363	00467
Ensembl ID		ENSG00000149798	ENSG00000135940
Uniprot IDs		O14613	A0A384NL93 P10606
PDB IDs			5Z62
Enriched GO Terms of Interacting Partners?
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