ARHGAP26 and PKN3

Number of citations of the paper that reports this interaction (PubMedID 11432776)
20

Data Source:
HPRD (in vivo, two hybrid)

		ARHGAP26	PKN3
Description		Rho GTPase activating protein 26	protein kinase N3
Image			No pdb structure
GO Annotations	Cellular Component	Cellular_component Cytosol Cytoskeleton Focal Adhesion	Nucleus Golgi Apparatus Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	GTPase Activator Activity Protein Binding Phospholipid Binding	Protein Kinase Activity Protein Serine/threonine Kinase Activity Calcium-dependent Protein Kinase C Activity Protein Binding ATP Binding Small GTPase Binding Protein Serine Kinase Activity
	Biological Process	Signal Transduction Nervous System Development Actin Cytoskeleton Organization Regulation Of Catalytic Activity Regulation Of Small GTPase Mediated Signal Transduction	Protein Phosphorylation Signal Transduction Epithelial Cell Migration Peptidyl-serine Phosphorylation Intracellular Signal Transduction
Pathways		RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RHOD GTPase cycle RHOQ GTPase cycle RHOJ GTPase cycle RAC3 GTPase cycle	RHO GTPases activate PKNs RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle
Drugs
Diseases
GWAS		Atrial fibrillation ( 29892015) Coronary artery disease ( 29212778) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Heel bone mineral density ( 30598549 28869591) Height ( 31562340) LDL cholesterol levels in HIV infection ( 33109212) Metabolite levels ( 23823483) Multiple sclerosis ( 31604244) Myocardial infarction ( 33532862) Night sleep phenotypes ( 27126917) PR interval ( 32439900) Pulse pressure ( 27841878) Septic shock resolution ( 32755526) Suicide attempt severity in mood disorders ( 33783297) Waist circumference ( 28552196)	Apolipoprotein B levels ( 32203549) Asthma ( 31361310) Axial length ( 24144296) Body mass index ( 26426971) Eating disorders (purging via substances) ( 23568457) Gamma glutamyl transferase levels ( 29403010 33339817) LDL cholesterol levels ( 32203549) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Low density lipoprotein cholesterol levels ( 32154731) Neutrophil count ( 32888494) Obesity-related traits ( 23251661) Platelet count ( 32888494) Plateletcrit ( 32888494 27863252) White blood cell count ( 32888494)
Interacting Genes		9 interacting genes: ACSL6 CDC42 CDC42EP2 INSR PKN1 PKN3 PTK2 RHOA SRPK1	9 interacting genes: ARHGAP10 ARHGAP26 GOLGA2 KRT31 MTUS2 PLD1 PNMA1 TFIP11 VPS52
Entrez ID		23092	29941
HPRD ID		05643	17856
Ensembl ID		ENSG00000145819	ENSG00000160447
Uniprot IDs		A0A0S2Z536 Q9UNA1	A0A024R8D6 Q6P5Z2
PDB IDs		1UGV
Enriched GO Terms of Interacting Partners?
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