CDC42EP2 and ARHGAP26

Number of citations of the paper that reports this interaction (PubMedID 26871637)
172

Data Source:
BioGRID (two hybrid)

		CDC42EP2	ARHGAP26
Description		CDC42 effector protein 2	Rho GTPase activating protein 26
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Endomembrane System Microtubule Cytoskeleton Membrane Phagocytic Vesicle	Cellular_component Cytosol Cytoskeleton Focal Adhesion
	Molecular Function	Opioid Peptide Activity GTPase Activator Activity Protein Binding Small GTPase Binding	GTPase Activator Activity Protein Binding Phospholipid Binding
	Biological Process	Actin Filament Organization Rho Protein Signal Transduction Regulation Of Cell Shape Actin Cytoskeleton Organization Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Pseudopodium Assembly Positive Regulation Of Protein-containing Complex Assembly Regulation Of Catalytic Activity Cellular Response To Interferon-gamma	Signal Transduction Nervous System Development Actin Cytoskeleton Organization Regulation Of Catalytic Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways		MAPK6/MAPK4 signaling CDC42 GTPase cycle RHOQ GTPase cycle	RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RHOD GTPase cycle RHOQ GTPase cycle RHOJ GTPase cycle RAC3 GTPase cycle
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494 27863252)	Atrial fibrillation ( 29892015) Coronary artery disease ( 29212778) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Heel bone mineral density ( 30598549 28869591) Height ( 31562340) LDL cholesterol levels in HIV infection ( 33109212) Metabolite levels ( 23823483) Multiple sclerosis ( 31604244) Myocardial infarction ( 33532862) Night sleep phenotypes ( 27126917) PR interval ( 32439900) Pulse pressure ( 27841878) Septic shock resolution ( 32755526) Suicide attempt severity in mood disorders ( 33783297) Waist circumference ( 28552196)
Interacting Genes		11 interacting genes: ARHGAP26 CASS4 CDC42 COX5B NEDD9 NME7 PICK1 RHOQ SEPTIN6 SEPTIN7 SNCA	9 interacting genes: ACSL6 CDC42 CDC42EP2 INSR PKN1 PKN3 PTK2 RHOA SRPK1
Entrez ID		10435	23092
HPRD ID		09363	05643
Ensembl ID		ENSG00000149798	ENSG00000145819
Uniprot IDs		O14613	A0A0S2Z536 Q9UNA1
PDB IDs			1UGV
Enriched GO Terms of Interacting Partners?
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