COPE and MBD1

Number of citations of the paper that reports this interaction (PubMedID 21653829)
98

Data Source:
BioGRID (two hybrid)

		COPE	MBD1
Description		COPI coat complex subunit epsilon	methyl-CpG binding domain protein 1
Image
GO Annotations	Cellular Component	Golgi Membrane Nucleoplasm Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol COPI Vesicle Coat Transport Vesicle	Chromatin Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Nuclear Speck
	Molecular Function	Structural Molecule Activity Protein Binding	DNA Binding Chromatin Binding Protein Binding Zinc Ion Binding Methyl-CpG Binding Double-stranded Methylated DNA Binding Unmethylated CpG Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Intra-Golgi Vesicle-mediated Transport Protein Transport Protein Localization To Axon	Transcription By RNA Polymerase II Heart Development Aging Response To Xenobiotic Stimulus Negative Regulation Of Gene Expression Neuron Differentiation Response To Nutrient Levels Response To Estradiol Response To Cocaine Regulation Of DNA Methylation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Astrocyte Differentiation
Pathways		COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic	SUMOylation of transcription cofactors
Drugs
Diseases
GWAS			Chronic lymphocytic leukemia ( 28165464)
Interacting Genes		16 interacting genes: ARF1 CDC42 CDC42EP3 COPA COPB1 COPB2 COPG1 COPG2 EFHC2 ERCC6 GDF15 MBD1 RCHY1 SCYL1 TMED10 WBP2	45 interacting genes: APP ATF7IP ATF7IP2 ATXN1L C1QBP CBX4 CBX5 CCDC136 CHAF1A COPE DVL3 ECT2 EEF1G GRN HDAC3 HIPK3 HTT JAG2 LTBP3 LTBP4 MDFI MEGF6 NELL1 NELL2 NOTCH1 NOTCH3 OASL PIAS1 PIAS2 POMGNT1 RNF2 SETDB1 SLC25A3 SMAD1 SMAD3 SMAD5 SMAD7 SMAD9 SNAPC2 SP1 SUV39H1 TENM1 TNC ZNF384 ZNF512B
Entrez ID		11316	4152
HPRD ID		06089	01133
Ensembl ID		ENSG00000105669	ENSG00000141644
Uniprot IDs		M0QXB4 O14579	A8K654 B4DI41 B4DUR3 Q9UIS9
PDB IDs		6TZT 6U3V	1D9N 1IG4 4D4W 5W9Q 6D1T
Enriched GO Terms of Interacting Partners?
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