COPE and WBP2

Number of citations of the paper that reports this interaction (PubMedID 27578003)
30

Data Source:
BioGRID (pull down)

		COPE	WBP2
Description		COPI coat complex subunit epsilon	WW domain binding protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleoplasm Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol COPI Vesicle Coat Transport Vesicle	Chromatin Nucleus Cytoplasm
	Molecular Function	Structural Molecule Activity Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Transcription Coactivator Activity Protein Binding Estrogen Receptor Binding Chromatin DNA Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Intra-Golgi Vesicle-mediated Transport Protein Transport Protein Localization To Axon	Response To Progesterone Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Response To Estrogen Establishment Of Protein Localization Positive Regulation Of Gene Expression, Epigenetic Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Progesterone Receptor Signaling Pathway Cellular Response To Estrogen Stimulus Positive Regulation Of Histone H3-K14 Acetylation
Pathways		COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS			Adult body size ( 32376654) Platelet count ( 32888494) Red blood cell count ( 32888494) White matter hyperintensities ( 32358547)
Interacting Genes		16 interacting genes: ARF1 CDC42 CDC42EP3 COPA COPB1 COPB2 COPG1 COPG2 EFHC2 ERCC6 GDF15 MBD1 RCHY1 SCYL1 TMED10 WBP2	53 interacting genes: ANAPC1 ANKRD13A ANKRD13D ARCN1 BAG3 CCT7 CLEC4G COPA COPB1 COPB2 COPE COPG1 CUEDC1 DDX17 EEF1B2 EPN2 ESR1 GRPEL1 H4C1 HOMER3 HUWE1 ITCH KRT18 KRT8 KRT9 LGALS8 MAGEA4 MAGI1 MYO6 NEDD4 NEDD4L PAX8 POLH RHBDD3 RNF168 RPS27A RPS3 SDHA SEPTIN3 SMAD5 TDP2 TOLLIP TOM1L2 UBA52 UBC UBE2E3 UBE3A UBQLN1 UIMC1 WWP1 WWP2 WWTR1 YAP1
Entrez ID		11316	23558
HPRD ID		06089	06097
Ensembl ID		ENSG00000105669	ENSG00000132471
Uniprot IDs		M0QXB4 O14579	A0A024R8L1 Q969T9
PDB IDs		6TZT 6U3V
Enriched GO Terms of Interacting Partners?
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