COPE and CDC42EP3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		COPE	CDC42EP3
Description		COPI coat complex subunit epsilon	CDC42 effector protein 3
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleoplasm Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol COPI Vesicle Coat Transport Vesicle	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Endomembrane System Actin Cytoskeleton
	Molecular Function	Structural Molecule Activity Protein Binding	Protein Binding Cytoskeletal Regulatory Protein Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Intra-Golgi Vesicle-mediated Transport Protein Transport Protein Localization To Axon	Signal Transduction Rho Protein Signal Transduction Regulation Of Cell Shape Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Pseudopodium Assembly
Pathways		COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic	MAPK6/MAPK4 signaling CDC42 GTPase cycle RHOQ GTPase cycle
Drugs
Diseases
GWAS			Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Cortical volume ( 32963231) Facial attractiveness (male raters) ( 30946739) HDL cholesterol levels in HIV infection ( 33109212) Height ( 28552196 20881960 23563607 31562340) Night sleep phenotypes ( 27126917) Rheumatoid arthritis ( 30891314) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Total ventricular volume (Alzheimer's disease interaction) ( 21116278) Waist circumference adjusted for body mass index ( 34021172) Youthful appearance (self-reported) ( 32339537)
Interacting Genes		16 interacting genes: ARF1 CDC42 CDC42EP3 COPA COPB1 COPB2 COPG1 COPG2 EFHC2 ERCC6 GDF15 MBD1 RCHY1 SCYL1 TMED10 WBP2	12 interacting genes: CDC42 COPE DAPK1 LRRK1 LRRK2 MFHAS1 RHOQ SEPTIN6 SEPTIN7 SNCA SRPK1 UMPS
Entrez ID		11316	10602
HPRD ID		06089	09364
Ensembl ID		ENSG00000105669	ENSG00000163171
Uniprot IDs		M0QXB4 O14579	Q9UKI2
PDB IDs		6TZT 6U3V
Enriched GO Terms of Interacting Partners?
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