MBD1 and EEF1G

Number of citations of the paper that reports this interaction (PubMedID 21653829)
98

Data Source:
BioGRID (two hybrid)

		MBD1	EEF1G
Description		methyl-CpG binding domain protein 1	eukaryotic translation elongation factor 1 gamma
Image
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Nuclear Speck	Nucleus Cytoplasm Endoplasmic Reticulum Cytosol Membrane Extracellular Exosome
	Molecular Function	DNA Binding Chromatin Binding Protein Binding Zinc Ion Binding Methyl-CpG Binding Double-stranded Methylated DNA Binding Unmethylated CpG Binding	Translation Elongation Factor Activity Protein Binding Cadherin Binding
	Biological Process	Transcription By RNA Polymerase II Heart Development Aging Response To Xenobiotic Stimulus Negative Regulation Of Gene Expression Neuron Differentiation Response To Nutrient Levels Response To Estradiol Response To Cocaine Regulation Of DNA Methylation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Astrocyte Differentiation	Translational Elongation Glutathione Metabolic Process Response To Virus
Pathways		SUMOylation of transcription cofactors	Eukaryotic Translation Elongation Signaling by ALK fusions and activated point mutants
Drugs
Diseases
GWAS		Chronic lymphocytic leukemia ( 28165464)	Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 28448500)
Interacting Genes		45 interacting genes: APP ATF7IP ATF7IP2 ATXN1L C1QBP CBX4 CBX5 CCDC136 CHAF1A COPE DVL3 ECT2 EEF1G GRN HDAC3 HIPK3 HTT JAG2 LTBP3 LTBP4 MDFI MEGF6 NELL1 NELL2 NOTCH1 NOTCH3 OASL PIAS1 PIAS2 POMGNT1 RNF2 SETDB1 SLC25A3 SMAD1 SMAD3 SMAD5 SMAD7 SMAD9 SNAPC2 SP1 SUV39H1 TENM1 TNC ZNF384 ZNF512B	97 interacting genes: ABCC9 ADAP2 AKT1 ANKRD28 ARF1 ARIH2 C11orf58 C1orf174 CARS1 CBX8 CCDC106 CCT7 CDC42 CDK2AP2 CDK5RAP2 CHFR CRELD1 CSTF2 CXCL13 DKC1 DLEU1 DLG4 DRD3 DYSF ECH1 EEF1B2 EEF1D EEF1DP3 EFNA1 EID2B ENOX1 FADS1 FEN1 FOXG1 GADD45A GADD45G GET4 GSK3B GSTO1 HARS1 HDAC5 HLTF HMOX2 HNRNPH3 ILF2 KARS1 KLHL18 LARS1 LINC01554 LZTS1 MBD1 MCRIP2 MED31 MLH1 MTNR1A MVD NADK NCK2 NDRG1 NUDT21 NUDT3 NUP85 OGFOD2 OGT PDCD5 PHACTR3 PLEKHA4 PLGRKT PSMD11 PTK2 PTPN4 PTPRF PTPRS RBM6 RECQL5 RGL2 RPL4P5 RPS28 SAT1 SFRP2 SKIL SLC22A2 SNAPIN SNRPD2 SUMO2 TNNT1 TP53I3 TRIB3 TRIM55 TRIM63 TUBB3 UCHL5 WDR33 YWHAG ZBED8 ZDHHC17 ZNF24
Entrez ID		4152	1937
HPRD ID		01133	11745
Ensembl ID		ENSG00000141644	ENSG00000254772
Uniprot IDs		A8K654 B4DI41 B4DUR3 Q9UIS9	P26641 Q53YD7
PDB IDs		1D9N 1IG4 4D4W 5W9Q 6D1T	1PBU 5DQS 5JPO
Enriched GO Terms of Interacting Partners?
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