PWP1 and CUL4B

Number of citations of the paper that reports this interaction (PubMedID 31973889)
8

Data Source:
BioGRID (affinity chromatography technology, pull down)

		PWP1	CUL4B
Description		PWP1 homolog, endonuclein	cullin 4B
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Chromosome Nucleolus Golgi Apparatus	Nucleoplasm Cytosol Cullin-RING Ubiquitin Ligase Complex Cul4B-RING E3 Ubiquitin Ligase Complex Extracellular Exosome Cul4-RING E3 Ubiquitin Ligase Complex
	Molecular Function	H4K20me3 Modified Histone Binding	Damaged DNA Binding Ubiquitin-protein Transferase Activity Protein Binding Ubiquitin Protein Ligase Binding
	Biological Process	Transcription, DNA-templated RRNA Processing Negative Regulation Of Peptidyl-serine Phosphorylation Of STAT Protein Histone H4-K20 Trimethylation Positive Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I Positive Regulation Of Stem Cell Differentiation	G1/S Transition Of Mitotic Cell Cycle Cellular Response To DNA Damage Stimulus Proteasomal Protein Catabolic Process Protein Ubiquitination SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Neuron Projection Development Histone H2A Monoubiquitination Ribosome Biogenesis UV-damage Excision Repair
Pathways			Recognition of DNA damage by PCNA-containing replication complex DNA Damage Recognition in GG-NER Formation of Incision Complex in GG-NER Dual Incision in GG-NER Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER Neddylation
Drugs
Diseases
GWAS		Acne (severe) ( 24927181)
Interacting Genes		9 interacting genes: APP CKAP4 CUL4B DAPK1 DCAF1 HOXA3 NFYA OGT SMURF1	55 interacting genes: AHR AMBRA1 APP AR BRWD1 BRWD3 CAND1 COMMD1 COP1 COPS2 COPS5 CRBN CUL4A DCAF10 DCAF11 DCAF12 DCAF15 DCAF16 DCAF17 DCAF4 DCAF5 DCAF6 DCUN1D1 DCUN1D4 DDA1 DDB1 DDB2 DET1 DNMT3B DTL ERCC8 ESR1 GLMN HUWE1 KPNA2 KPNA4 KPNB1 NEDD8 PHIP PLS3 PRDX3 PTEN PWP1 RBX1 RNF7 SALL2 SIN3A SRC ST7 TBL3 TRPC4AP UBC UBE2D3 WDTC1 ZMAT4
Entrez ID		11137	8450
HPRD ID		11464	02251
Ensembl ID		ENSG00000136045	ENSG00000158290
Uniprot IDs		A0A024RBH5 B4DJV5 Q13610	K4DI93 Q13620
PDB IDs			2DO7 4A0C 4A0L 4A64
Enriched GO Terms of Interacting Partners?
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