PWP1 and HOXA3

Number of citations of the paper that reports this interaction (PubMedID 20211142)
361

Data Source:
BioGRID (two hybrid)

		PWP1	HOXA3
Description		PWP1 homolog, endonuclein	homeobox A3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Chromosome Nucleolus Golgi Apparatus	Chromatin Nucleus Nucleoplasm
	Molecular Function	H4K20me3 Modified Histone Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding HMG Box Domain Binding
	Biological Process	Transcription, DNA-templated RRNA Processing Negative Regulation Of Peptidyl-serine Phosphorylation Of STAT Protein Histone H4-K20 Trimethylation Positive Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I Positive Regulation Of Stem Cell Differentiation	Angiogenesis Blood Vessel Remodeling Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Cell Population Proliferation Anterior/posterior Pattern Specification Specification Of Animal Organ Position Gene Expression Glossopharyngeal Nerve Morphogenesis Thyroid Gland Development Thymus Development Animal Organ Formation Embryonic Skeletal System Morphogenesis Cartilage Development Parathyroid Gland Development
Pathways			Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases
GWAS		Acne (severe) ( 24927181)	Body shape index ( 34021172) Chronic venous disease ( 28374850) Diastolic blood pressure ( 27618448) Hypertension ( 27618448 30487518) Lymphocyte counts ( 32888494) Mean arterial pressure ( 27618448) Monocyte count ( 32888494 27863252) Pulse pressure ( 30487518) Systolic blood pressure ( 28135244 27618448 30487518) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) White blood cell count ( 32888494)
Interacting Genes		9 interacting genes: APP CKAP4 CUL4B DAPK1 DCAF1 HOXA3 NFYA OGT SMURF1	10 interacting genes: ALX4 ARPC3 POT1 PWP1 RCHY1 SEC23B SOX10 TERF1 TINF2 ZDHHC17
Entrez ID		11137	3200
HPRD ID		11464	00842
Ensembl ID		ENSG00000136045	ENSG00000105997
Uniprot IDs		A0A024RBH5 B4DJV5 Q13610	A0A024RA33 A4D182 B3KPN8 O43365
PDB IDs
Enriched GO Terms of Interacting Partners?
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