CUL4B and PHIP

Number of citations of the paper that reports this interaction (PubMedID 31973889)
8

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, pull down)

		CUL4B	PHIP
Description		cullin 4B	pleckstrin homology domain interacting protein
Image
GO Annotations	Cellular Component	Nucleoplasm Cytosol Cullin-RING Ubiquitin Ligase Complex Cul4B-RING E3 Ubiquitin Ligase Complex Extracellular Exosome Cul4-RING E3 Ubiquitin Ligase Complex	Nucleus
	Molecular Function	Damaged DNA Binding Ubiquitin-protein Transferase Activity Protein Binding Ubiquitin Protein Ligase Binding	Insulin Receptor Binding Protein Binding Lysine-acetylated Histone Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Cellular Response To DNA Damage Stimulus Proteasomal Protein Catabolic Process Protein Ubiquitination SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Neuron Projection Development Histone H2A Monoubiquitination Ribosome Biogenesis UV-damage Excision Repair	Regulation Of Protein Phosphorylation Regulation Of Transcription By RNA Polymerase II Cytoskeleton Organization Positive Regulation Of Cell Population Proliferation Insulin Receptor Signaling Pathway Regulation Of Cell Shape Regulation Of Cell Morphogenesis Negative Regulation Of Apoptotic Process Positive Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Positive Regulation Of Mitotic Nuclear Division Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		Recognition of DNA damage by PCNA-containing replication complex DNA Damage Recognition in GG-NER Formation of Incision Complex in GG-NER Dual Incision in GG-NER Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER Neddylation	RHOBTB2 GTPase cycle
Drugs
Diseases
GWAS			Diastolic blood pressure ( 27841878 27618448) Intelligence (MTAG) ( 29326435) LDL cholesterol levels x loop diuretics use interaction ( 31806883) Mean arterial pressure ( 27618448) SjÃ¶gren's syndrome ( 24097067) Systolic blood pressure ( 27841878 30578418)
Interacting Genes		55 interacting genes: AHR AMBRA1 APP AR BRWD1 BRWD3 CAND1 COMMD1 COP1 COPS2 COPS5 CRBN CUL4A DCAF10 DCAF11 DCAF12 DCAF15 DCAF16 DCAF17 DCAF4 DCAF5 DCAF6 DCUN1D1 DCUN1D4 DDA1 DDB1 DDB2 DET1 DNMT3B DTL ERCC8 ESR1 GLMN HUWE1 KPNA2 KPNA4 KPNB1 NEDD8 PHIP PLS3 PRDX3 PTEN PWP1 RBX1 RNF7 SALL2 SIN3A SRC ST7 TBL3 TRPC4AP UBC UBE2D3 WDTC1 ZMAT4	4 interacting genes: CUL4B IRS1 STMN4 TUBB3
Entrez ID		8450	55023
HPRD ID		02251	10152
Ensembl ID		ENSG00000158290	ENSG00000146247
Uniprot IDs		K4DI93 Q13620	Q8WWQ0
PDB IDs		2DO7 4A0C 4A0L 4A64	3MB3 5ENB 5ENC 5ENE 5ENF 5ENH 5ENI 5ENJ 5RJI 5RJJ 5RJK 5RJL 5RJM 5RJN 5RJO 5RJP 5RJQ 5RJR 5RJS 5RJT 5RJU 5RJV 5RJW 5RJX 5RJY 5RJZ 5RK0 5RK1 5RK2 5RK3 5RK4 5RK5 5RK6 5RK7 5RK8 5RK9 5RKA 5RKB 5RKC 5RKD 5RKE 5RKF 5RKG 5RKH 5RKI 5RKJ 5RKK 5RKL 5RKM 5RKN 5RKO 5RKP 5RKQ 5RKR 5RKS 5RKT 5RKU 5RKV 5RKW 5RKX 5RKY 5S8C 5S8D 5S8E 5S8F 5S8G 5S8H 5S8I 5S8J 5S8K 5S8L 5S8M 5S8N 5S8O 5S8P 5S8Q 5S8R 5S8S 5S8T 5S8U 5S8V 5S8W 5S8X 5S8Y 5S8Z 5S90 5S91 5S92 5S93 5S94 5S95 5S96 5S97 5S98 5S99 5S9A 5S9B 5S9C 5S9D 5S9E 5S9F 5S9G 5S9H 5S9I 5S9J 7AV8 7AV9 7BBO 7BBP
Enriched GO Terms of Interacting Partners?
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