PWP1 and DCAF1

Number of citations of the paper that reports this interaction (PubMedID 33355139)
1

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, enzymatic study)

		PWP1	DCAF1
Description		PWP1 homolog, endonuclein	DDB1 and CUL4 associated factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Chromosome Nucleolus Golgi Apparatus	Fibrillar Center Nucleus Nucleoplasm Cytoplasm Cul4-RING E3 Ubiquitin Ligase Complex
	Molecular Function	H4K20me3 Modified Histone Binding	Protein Binding ATP Binding Estrogen Receptor Binding Protein Serine Kinase Activity Histone Kinase Activity (H2A-T120 Specific)
	Biological Process	Transcription, DNA-templated RRNA Processing Negative Regulation Of Peptidyl-serine Phosphorylation Of STAT Protein Histone H4-K20 Trimethylation Positive Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I Positive Regulation Of Stem Cell Differentiation	Negative Regulation Of Transcription By RNA Polymerase II Protein Ubiquitination B Cell Differentiation V(D)J Recombination Cell Competition In A Multicellular Organism Histone H2A-T120 Phosphorylation
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Acne (severe) ( 24927181)	Asthma ( 32296059)
Interacting Genes		9 interacting genes: APP CKAP4 CUL4B DAPK1 DCAF1 HOXA3 NFYA OGT SMURF1	22 interacting genes: ATM ATR CCP110 EXO1 FOXM1 H3-3A H3-4 H3C1 HLTF IMPDH2 KATNA1 NF2 PRKDC PWP1 PYGO2 RAG1 RBX1 SAMHD1 TET2 TP53 UBE2D2 UBE2D3
Entrez ID		11137	9730
HPRD ID		11464	11674
Ensembl ID		ENSG00000136045	ENSG00000145041
Uniprot IDs		A0A024RBH5 B4DJV5 Q13610	Q9Y4B6
PDB IDs			3WA0 4CC9 4P7I 4PXW 4Z8L 5AJA 5JK7 6N45
Enriched GO Terms of Interacting Partners?
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