CCR9 and SAP130

Number of citations of the paper that reports this interaction (PubMedID 28298427)
23

Data Source:
BioGRID (two hybrid)

		CCR9	SAP130
Description		C-C motif chemokine receptor 9	Sin3A associated protein 130
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Cell Surface	Nuclear Speck Sin3-type Complex
	Molecular Function	Chemokine Receptor Activity C-C Chemokine Receptor Activity C-C Chemokine Binding
	Biological Process	CD8-positive, Gamma-delta Intraepithelial T Cell Differentiation Chemotaxis Immune Response Cellular Defense Response G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Calcium-mediated Signaling Cell Chemotaxis Chemokine-mediated Signaling Pathway	Negative Regulation Of Transcription By RNA Polymerase II
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events	HATs acetylate histones NoRC negatively regulates rRNA expression
Drugs		Vercirnon
Diseases
GWAS		Celiac disease ( 20190752) Liver enzyme levels (alkaline phosphatase) ( 33972514) Severe COVID-19 infection with respiratory failure (analysis I) ( 32558485) Severe COVID-19 infection with respiratory failure (analysis II) ( 32558485)	Anti-saccade response ( 29064472) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
Interacting Genes		20 interacting genes: ADGRG1 AIG1 CCL25 CD81 DGAT1 G6PC3 HLA-A KDELR1 NEU1 OSTC RHBDD2 SAP130 SCAMP4 SPNS1 TMC6 TMEM33 TRPM4 TSPAN7 TTYH1 YWHAE	12 interacting genes: ARID4B CCR9 CUL2 GPS1 IWS1 MARCO MECOM MYC NIFK SFT2D3 SGK2 SMAD3
Entrez ID		10803	79595
HPRD ID		09200	18015
Ensembl ID		ENSG00000173585	ENSG00000136715
Uniprot IDs		B2R734 P51686	A0A2R8YDB8 H7BXF5 Q96DP1 Q9H0E3
PDB IDs		5LWE
Enriched GO Terms of Interacting Partners?
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