CCR9 and TTYH1

Number of citations of the paper that reports this interaction (PubMedID 28298427)
23

Data Source:
BioGRID (two hybrid)

		CCR9	TTYH1
Description		C-C motif chemokine receptor 9	tweety family member 1
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Cell Surface	Plasma Membrane Integral Component Of Membrane Smooth Endoplasmic Reticulum Membrane Chloride Channel Complex
	Molecular Function	Chemokine Receptor Activity C-C Chemokine Receptor Activity C-C Chemokine Binding	Intracellular Calcium Activated Chloride Channel Activity Chloride Channel Activity Iron Ion Transmembrane Transporter Activity Protein Binding Volume-sensitive Chloride Channel Activity
	Biological Process	CD8-positive, Gamma-delta Intraepithelial T Cell Differentiation Chemotaxis Immune Response Cellular Defense Response G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Calcium-mediated Signaling Cell Chemotaxis Chemokine-mediated Signaling Pathway	Chloride Transport Iron Ion Transport Cell Adhesion Ion Transmembrane Transport Iron Ion Transmembrane Transport
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs		Vercirnon
Diseases
GWAS		Celiac disease ( 20190752) Liver enzyme levels (alkaline phosphatase) ( 33972514) Severe COVID-19 infection with respiratory failure (analysis I) ( 32558485) Severe COVID-19 infection with respiratory failure (analysis II) ( 32558485)	Blood trace element (Se levels) ( 23720494) Idiopathic pulmonary fibrosis ( 29066090)
Interacting Genes		20 interacting genes: ADGRG1 AIG1 CCL25 CD81 DGAT1 G6PC3 HLA-A KDELR1 NEU1 OSTC RHBDD2 SAP130 SCAMP4 SPNS1 TMC6 TMEM33 TRPM4 TSPAN7 TTYH1 YWHAE	6 interacting genes: CCR9 DRD2 GPR37 HTR6 TMEM60 USP54
Entrez ID		10803	57348
HPRD ID		09200	12043
Ensembl ID		ENSG00000173585	ENSG00000167614
Uniprot IDs		B2R734 P51686	Q9H313
PDB IDs		5LWE
Enriched GO Terms of Interacting Partners?
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