SAP130 and IWS1

		SAP130	IWS1
Description		Sin3A associated protein 130	interacts with SUPT6H, CTD assembly factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Speck Sin3-type Complex	Nucleus Nucleoplasm
	Molecular Function		Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II	MRNA Processing RNA Splicing Regulation Of MRNA Export From Nucleus Poly(A)+ MRNA Export From Nucleus Regulation Of MRNA Processing Regulation Of Histone H4 Acetylation Regulation Of Histone H3-K36 Trimethylation
Pathways		HATs acetylate histones NoRC negatively regulates rRNA expression	Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS		Anti-saccade response ( 29064472) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)	Cardiac troponin-I levels ( 31014085)
Interacting Genes		12 interacting genes: ARID4B CCR9 CUL2 GPS1 IWS1 MARCO MECOM MYC NIFK SFT2D3 SGK2 SMAD3	11 interacting genes: AKT1 AKT3 CSNK2A1 ERCC6 ERICH2 KRTAP10-3 POLR2A SAP130 STAT2 SUPT6H TCEA1
Entrez ID		79595	55677
HPRD ID		18015	07639
Ensembl ID		ENSG00000136715	ENSG00000163166
Uniprot IDs		A0A2R8YDB8 H7BXF5 Q96DP1 Q9H0E3	Q96ST2
PDB IDs			6EMR
Enriched GO Terms of Interacting Partners?
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