CCR9 and DGAT1

Number of citations of the paper that reports this interaction (PubMedID 28298427)
23

Data Source:
BioGRID (two hybrid)

		CCR9	DGAT1
Description		C-C motif chemokine receptor 9	diacylglycerol O-acyltransferase 1
Image
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Cell Surface	Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane Specific Granule Membrane
	Molecular Function	Chemokine Receptor Activity C-C Chemokine Receptor Activity C-C Chemokine Binding	2-acylglycerol O-acyltransferase Activity Diacylglycerol O-acyltransferase Activity Protein Binding O-acyltransferase Activity Acyltransferase Activity Identical Protein Binding Retinol O-fatty-acyltransferase Activity
	Biological Process	CD8-positive, Gamma-delta Intraepithelial T Cell Differentiation Chemotaxis Immune Response Cellular Defense Response G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Calcium-mediated Signaling Cell Chemotaxis Chemokine-mediated Signaling Pathway	Monoacylglycerol Biosynthetic Process Triglyceride Metabolic Process Triglyceride Biosynthetic Process Lipid Storage Very-low-density Lipoprotein Particle Assembly Long-chain Fatty-acyl-CoA Metabolic Process Retinol Metabolic Process Diacylglycerol Metabolic Process Fatty Acid Homeostasis
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events	Acyl chain remodeling of DAG and TAG Neutrophil degranulation Triglyceride biosynthesis
Drugs		Vercirnon
Diseases
GWAS		Celiac disease ( 20190752) Liver enzyme levels (alkaline phosphatase) ( 33972514) Severe COVID-19 infection with respiratory failure (analysis I) ( 32558485) Severe COVID-19 infection with respiratory failure (analysis II) ( 32558485)	Dupuytren's disease ( 28886342) Fasting glucose ( 34059833)
Interacting Genes		20 interacting genes: ADGRG1 AIG1 CCL25 CD81 DGAT1 G6PC3 HLA-A KDELR1 NEU1 OSTC RHBDD2 SAP130 SCAMP4 SPNS1 TMC6 TMEM33 TRPM4 TSPAN7 TTYH1 YWHAE	4 interacting genes: CCR9 CD1A GABRA4 GPAA1
Entrez ID		10803	8694
HPRD ID		09200	05360
Ensembl ID		ENSG00000173585	ENSG00000185000
Uniprot IDs		B2R734 P51686	O75907
PDB IDs		5LWE	6VP0 6VYI 6VZ1
Enriched GO Terms of Interacting Partners?
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