SAP130 and MARCO

		SAP130	MARCO
Description		Sin3A associated protein 130	macrophage receptor with collagenous structure
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Speck Sin3-type Complex	Collagen Trimer Intracellular Anatomical Structure Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Endocytic Vesicle Membrane
	Molecular Function		Amyloid-beta Binding G Protein-coupled Receptor Binding Transmembrane Signaling Receptor Activity Scavenger Receptor Activity Cargo Receptor Activity Pattern Recognition Receptor Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II	Positive Regulation Of Protein Phosphorylation Endocytosis Receptor-mediated Endocytosis Phagocytosis, Engulfment Cell Surface Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Apoptotic Cell Clearance Innate Immune Response Positive Regulation Of ERK1 And ERK2 Cascade Amyloid-beta Clearance
Pathways		HATs acetylate histones NoRC negatively regulates rRNA expression	Scavenging by Class A Receptors Scavenging by Class A Receptors
Drugs			Titanium dioxide Silicon dioxide
Diseases
GWAS		Anti-saccade response ( 29064472) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)	Lung function (FVC) ( 30061609) Medication use (adrenergics, inhalants) ( 31015401) Triglyceride levels ( 32203549)
Interacting Genes		12 interacting genes: ARID4B CCR9 CUL2 GPS1 IWS1 MARCO MECOM MYC NIFK SFT2D3 SGK2 SMAD3	4 interacting genes: NAT14 SAP130 SCGB3A1 SCGB3A2
Entrez ID		79595	8685
HPRD ID		18015	05337
Ensembl ID		ENSG00000136715	ENSG00000019169
Uniprot IDs		A0A2R8YDB8 H7BXF5 Q96DP1 Q9H0E3	Q4ZG40 Q9UEW3
PDB IDs
Enriched GO Terms of Interacting Partners?
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