TANK and TBK1

  • Number of citations of the paper that reports this interaction (PubMedID 10581243)
  • 197
  • Data Source:
  • HPRD (two hybrid, in vivo)

TANK

TBK1

Description TRAF family member associated NFKB activator TANK binding kinase 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alcohol consumption ( 27911795)
  • Brain morphology (min-P) ( 32665545)
  • Brain morphology (MOSTest) ( 32665545)
  • Chronotype ( 30696823)
  • Cortical surface area (MOSTest) ( 32665545)
  • Cortical thickness (MOSTest) ( 32665545)
  • Dietary macronutrient intake ( 23372041)
  • Educational attainment ( 25201988)
  • Educational attainment (years of education) ( 23722424)
  • Extremely high intelligence ( 29520040)
  • General cognitive ability ( 29844566)
  • Household income (MTAG) ( 31844048)
  • Obesity-related traits ( 23251661)
  • Presence of antiphospholipid antibodies ( 23509613)
  • Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 3 peripheral neuropathy) ( 24554482)
  • Smoking status (ever vs never smokers) ( 30643258)
  • Subcortical volume (min-P) ( 32665545)
  • Subcortical volume (MOSTest) ( 32665545)
  • Subcutaneous adipose tissue ( 22589738)
  • Tourette syndrome ( 30818990)
  • Treatment response for severe sepsis ( 22310353)
  • Weight ( 31647587)
  • Amyotrophic lateral sclerosis ( 29566793 27455348)
  • High light scatter reticulocyte count ( 32888494)
  • High light scatter reticulocyte percentage of red cells ( 32888494)
  • Lung adenocarcinoma ( 28604730)
  • Reticulocyte count ( 32888494)
  • Reticulocyte fraction of red cells ( 32888494)
Interacting Genes 33 interacting genes: AIMP2 APBA3 APP ATP6V1H BIK CD40 CHUK COPB1 FBLN1 HLA-C IKBKB IKBKE IKBKG INPP5K KPNA2 LAMC1 LRP2 MAP4K5 MARCHF5 PLK1 RACGAP1 SDC4 SMAD3 SRSF11 TBK1 TP53BP2 TRAF1 TRAF2 TRAF3 TRAF6 TSC1 USP7 ZC3H12A 53 interacting genes: AGAP2 AGO2 APP ATG9A AVIL AZI2 CALCOCO2 CDC37 CDC42BPG CRTC1 CYLD HSP90AA1 HSP90AB1 IKBKB IKBKG IRF3 IRF5 IRF7 MAP1LC3B MARCHF9 MAVS MBP MIB2 MPP3 MTPAP NCK1 NEDD4 NFKBIA PROS1 PTPRD RELA RIPK1 RNF128 RPS6KB1 SCN7A SIKE1 SMCR8 SMURF1 SOCS2 SQSTM1 STX11 TANK TICAM1 TRAF2 TRAF3 TRAF3IP2 TRAF5 TRIM21 TRIM27 TXLNG UBQLN2 XIAP YAF2
Entrez ID 10010 29110
HPRD ID 04870 05322
Ensembl ID ENSG00000136560 ENSG00000183735
Uniprot IDs B2R7S3 Q6NW12 Q92844 Q9UHD2
PDB IDs 1KZZ 1L0A 5H10 4EFO 4EUT 4EUU 4IM0 4IM2 4IM3 4IW0 4IWO 4IWP 4IWQ 5EOA 5EOF 5EP6 5W5V 6BNY 6BOD 6BOE 6CQ0 6CQ4 6CQ5 6NT9 6O8B 6RSR 6RST 6RSU
Enriched GO Terms of Interacting Partners?
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