Description |
TRAF family member associated NFKB activator |
inhibitor of nuclear factor kappa B kinase subunit beta |
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GO Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
- Alcohol consumption ( 27911795)
- Brain morphology (min-P) ( 32665545)
- Brain morphology (MOSTest) ( 32665545)
- Chronotype ( 30696823)
- Cortical surface area (MOSTest) ( 32665545)
- Cortical thickness (MOSTest) ( 32665545)
- Dietary macronutrient intake ( 23372041)
- Educational attainment ( 25201988)
- Educational attainment (years of education) ( 23722424)
- Extremely high intelligence ( 29520040)
- General cognitive ability ( 29844566)
- Household income (MTAG) ( 31844048)
- Obesity-related traits ( 23251661)
- Presence of antiphospholipid antibodies ( 23509613)
- Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 3 peripheral neuropathy) ( 24554482)
- Smoking status (ever vs never smokers) ( 30643258)
- Subcortical volume (min-P) ( 32665545)
- Subcortical volume (MOSTest) ( 32665545)
- Subcutaneous adipose tissue ( 22589738)
- Tourette syndrome ( 30818990)
- Treatment response for severe sepsis ( 22310353)
- Weight ( 31647587)
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Interacting Genes |
33 interacting genes:
AIMP2
APBA3
APP
ATP6V1H
BIK
CD40
CHUK
COPB1
FBLN1
HLA-C
IKBKB
IKBKE
IKBKG
INPP5K
KPNA2
LAMC1
LRP2
MAP4K5
MARCHF5
PLK1
RACGAP1
SDC4
SMAD3
SRSF11
TBK1
TP53BP2
TRAF1
TRAF2
TRAF3
TRAF6
TSC1
USP7
ZC3H12A
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88 interacting genes:
ACVR1
AKT1
AURKA
CASP8
CCAR2
CDC37
CFLAR
CHUK
COPS3
COPS4
COPS5
CSF2RA
CSF2RB
CTNNB1
CUEDC2
E2F4
EIF2AK2
EIF2AK3
ELP1
FAF1
FANCA
FOXO3
GLI1
HSP90AA1
HSP90AB1
HTT
IKBKG
IRS1
JUN
KLHL21
MAP3K1
MAP3K11
MAP3K13
MAP3K14
MAP3K3
MAP3K7
MAVS
MTDH
NAA20
NCOA3
NEDD4L
NFKB1
NFKB2
NFKBIA
NFKBIB
NR2C2
PEBP1
PELI1
PLK1
PPARG
PPM1B
PPP2R3C
PRKCA
PRKCB
PRKCD
PRKCE
PRKCQ
PRKCZ
PRKDC
RELA
RICTOR
RIPK1
ROCK1
SASH1
SQSTM1
SRC
STAP2
TAB2
TANK
TBK1
TFAP2C
TGFBR1
TNFAIP3
TNFRSF1A
TP53
TP73
TRAF1
TRAF2
TRAF3IP2
TRIM21
TRIM27
TRPC4AP
TSC1
TWIST1
UBB
UBC
VHL
YWHAB
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Entrez ID |
10010 |
3551 |
HPRD ID |
04870 |
04462 |
Ensembl ID |
ENSG00000136560
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ENSG00000104365
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Uniprot IDs |
B2R7S3
Q6NW12
Q92844
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O14920
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PDB IDs |
1KZZ
1L0A
5H10
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3BRT
3BRV
4E3C
4KIK
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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