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PER2 and TPT1
Data Source:
BioGRID
(two hybrid)
PER2
TPT1
Description
period circadian regulator 2
tumor protein, translationally-controlled 1
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Cytosol
Perinuclear Region Of Cytoplasm
Spindle Pole
Extracellular Space
Nucleus
Cytoplasm
Multivesicular Body
Cytosol
Cytoplasmic Microtubule
Extracellular Exosome
Molecular Function
Transcription Regulatory Region Sequence-specific DNA Binding
Transcription Corepressor Binding
Transcription Coactivator Activity
Protein Binding
RNA Binding
Calcium Ion Binding
Protein Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Response To Ischemia
Glycogen Biosynthetic Process
Gluconeogenesis
Fatty Acid Metabolic Process
Circadian Rhythm
Regulation Of Vasoconstriction
Lactate Biosynthetic Process
Negative Regulation Of Protein Ubiquitination
Circadian Regulation Of Gene Expression
Regulation Of Circadian Rhythm
Negative Regulation Of Circadian Rhythm
Entrainment Of Circadian Clock By Photoperiod
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Regulation Of Neurogenesis
Regulation Of Insulin Secretion
White Fat Cell Differentiation
Regulation Of Cell Cycle
Regulation Of Glutamate Uptake Involved In Transmission Of Nerve Impulse
Negative Regulation Of Fat Cell Proliferation
Histone H3 Deacetylation
Circadian Regulation Of Translation
Positive Regulation Of Cold-induced Thermogenesis
Negative Regulation Of Transcription Regulatory Region DNA Binding
Calcium Ion Transport
Cellular Calcium Ion Homeostasis
Response To Virus
Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Pathways
Circadian Clock
Drugs
Calcium citrate
Calcium Phosphate
Calcium phosphate dihydrate
Diseases
Familial advanced sleep phase syndrome
GWAS
Chronotype (
26955885
30696823
27494321
)
Morning vs. evening chronotype (
26955885
26835600
27494321
)
Type 2 diabetes (
25760438
)
Interacting Genes
25 interacting genes:
BHLHE41
BTRC
CLOCK
CRY1
CRY2
CSNK1D
CSNK1E
CSNK2B
DELEC1
ELOA
LENG8
LMO4
MDM2
MLH1
PER1
PER3
RORC
TIMELESS
TP53
TPT1
TPTEP2-CSNK1E
UBE2D1
UBE2D2
UBE2D3
UBL4A
30 interacting genes:
APP
ATP1A1
ATP1A2
BCL2L1
CALM1
DBN1
EEF1A1
EEF1A2
EEF1B2
EEF1D
FANCA
HSPB1
IKBKG
LIG4
MCL1
MCPH1
MDM2
MLC1
NKX3-1
NOTCH3
PER2
PLK1
RBBP6
RPLP1
SNX6
SPP1
STEAP3
TRIP13
TUBB2A
VHL
Entrez ID
8864
7178
HPRD ID
04575
15979
Ensembl ID
ENSG00000132326
ENSG00000133112
Uniprot IDs
O15055
A0A024RDY2
A0A0B4J2C3
A0A0P1J1R0
P13693
PDB IDs
6OF7
1YZ1
2HR9
3EBM
4Z9V
5O9L
5O9M
6IZB
6IZE
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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