TPT1 and EEF1D

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		TPT1	EEF1D
Description		tumor protein, translationally-controlled 1	eukaryotic translation elongation factor 1 delta
Image
GO Annotations	Cellular Component	Spindle Pole Extracellular Space Nucleus Cytoplasm Multivesicular Body Cytosol Cytoplasmic Microtubule Extracellular Exosome	Fibrillar Center Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Cytosol Eukaryotic Translation Elongation Factor 1 Complex
	Molecular Function	RNA Binding Calcium Ion Binding Protein Binding	DNA Binding Translation Elongation Factor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding Translation Factor Activity, RNA Binding Cadherin Binding
	Biological Process	Calcium Ion Transport Cellular Calcium Ion Homeostasis Response To Virus Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage	Translational Elongation Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Catalytic Activity Cellular Response To Ionizing Radiation
Pathways			Eukaryotic Translation Elongation
Drugs		Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases
GWAS		Type 2 diabetes ( 25760438)	Schizophrenia ( 31268507)
Interacting Genes		30 interacting genes: APP ATP1A1 ATP1A2 BCL2L1 CALM1 DBN1 EEF1A1 EEF1A2 EEF1B2 EEF1D FANCA HSPB1 IKBKG LIG4 MCL1 MCPH1 MDM2 MLC1 NKX3-1 NOTCH3 PER2 PLK1 RBBP6 RPLP1 SNX6 SPP1 STEAP3 TRIP13 TUBB2A VHL	41 interacting genes: ABTB1 ALX1 APP ARHGAP21 ASCC2 ATG7 CAMSAP2 CD48 CDK1 CDK9 CRMP1 CSNK2A1 CTBP1 CTBP2 ECH1 EEF1G EPRS1 ERP27 FKBP6 FOS FRA10AC1 GARS1 HEXD HSF1 KARS1 KTN1 MAP1B NR2F1 POT1 PRKCA RELA RNF40 RPS6KA1 SIAH1 SIAH2 SQSTM1 TERF1 TINF2 TPT1 UBE2A VARS1
Entrez ID		7178	1936
HPRD ID		15979	00560
Ensembl ID		ENSG00000133112	ENSG00000104529
Uniprot IDs		A0A024RDY2 A0A0B4J2C3 A0A0P1J1R0 P13693	B2RAR6 D3DWK1 P29692
PDB IDs		1YZ1 2HR9 3EBM 4Z9V 5O9L 5O9M 6IZB 6IZE	2MVM 2MVN 2N51 5JPO
Enriched GO Terms of Interacting Partners?
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