EEF1D and EPRS1

Data Source:
BioGRID (pull down)

		EEF1D	EPRS1
Description		eukaryotic translation elongation factor 1 delta	glutamyl-prolyl-tRNA synthetase 1
Image
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Cytosol Eukaryotic Translation Elongation Factor 1 Complex	Cytoplasm Cytosol Plasma Membrane Membrane Aminoacyl-tRNA Synthetase Multienzyme Complex GAIT Complex Ribonucleoprotein Complex
	Molecular Function	DNA Binding Translation Elongation Factor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding Translation Factor Activity, RNA Binding Cadherin Binding	Glutamate-tRNA Ligase Activity Proline-tRNA Ligase Activity Protein Binding ATP Binding Zinc Ion Binding RNA Stem-loop Binding Identical Protein Binding Protein Homodimerization Activity GTPase Binding
	Biological Process	Translational Elongation Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Catalytic Activity Cellular Response To Ionizing Radiation	TRNA Aminoacylation For Protein Translation Glutamyl-tRNA Aminoacylation Prolyl-tRNA Aminoacylation Negative Regulation Of Translation Cellular Response To Insulin Stimulus Protein-containing Complex Assembly Cellular Response To Interferon-gamma Regulation Of Long-chain Fatty Acid Import Into Cell
Pathways		Eukaryotic Translation Elongation	Selenoamino acid metabolism Cytosolic tRNA aminoacylation tRNA modification in the nucleus and cytosol
Drugs			Glutamic acid Proline 5'-O-(L-Prolylsulfamoyl)adenosine 5'-O-(L-Cysteinylsulfamoyl)adenosine 5'-O-(N-(Alanyl)sulfamoyl)adenosine
Diseases
GWAS		Schizophrenia ( 31268507)
Interacting Genes		41 interacting genes: ABTB1 ALX1 APP ARHGAP21 ASCC2 ATG7 CAMSAP2 CD48 CDK1 CDK9 CRMP1 CSNK2A1 CTBP1 CTBP2 ECH1 EEF1G EPRS1 ERP27 FKBP6 FOS FRA10AC1 GARS1 HEXD HSF1 KARS1 KTN1 MAP1B NR2F1 POT1 PRKCA RELA RNF40 RPS6KA1 SIAH1 SIAH2 SQSTM1 TERF1 TINF2 TPT1 UBE2A VARS1	89 interacting genes: AIMP2 ARL4D CDC42 DUS2 DUX4 EEF1D ESR1 HSP90AA1 IARS1 LINC01554 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I NEDD4 NELFCD PTEN RARS1 SUMO2 SYNCRIP TAB1
Entrez ID		1936	2058
HPRD ID		00560	00703
Ensembl ID		ENSG00000104529	ENSG00000136628
Uniprot IDs		B2RAR6 D3DWK1 P29692	P07814
PDB IDs		2MVM 2MVN 2N51 5JPO	1FYJ 4HVC 4K86 4K87 4K88 5A1N 5A34 5A5H 5BMU 5V58 5VAD 5Y6L 6IY6
Enriched GO Terms of Interacting Partners?
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