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EEF1D and RNF40
Data Source:
BioGRID
(pull down)
EEF1D
RNF40
Description
eukaryotic translation elongation factor 1 delta
ring finger protein 40
Image
No pdb structure
GO Annotations
Cellular Component
Fibrillar Center
Nucleus
Nucleoplasm
Cytoplasm
Endoplasmic Reticulum
Cytosol
Eukaryotic Translation Elongation Factor 1 Complex
Ubiquitin Ligase Complex
Nucleus
Nucleoplasm
Cytosol
Membrane
Extrinsic Component Of Membrane
HULC Complex
Neuron Projection
Axon Terminus
Molecular Function
DNA Binding
Translation Elongation Factor Activity
Guanyl-nucleotide Exchange Factor Activity
Protein Binding
Translation Factor Activity, RNA Binding
Cadherin Binding
MRNA 3'-UTR Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Syntaxin-1 Binding
Ubiquitin Conjugating Enzyme Binding
Ubiquitin Protein Ligase Binding
Protein Homodimerization Activity
Protein-containing Complex Binding
Metal Ion Binding
Biological Process
Translational Elongation
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Regulation Of Catalytic Activity
Cellular Response To Ionizing Radiation
Ubiquitin-dependent Protein Catabolic Process
Regulation Of Mitotic Cell Cycle
Histone Monoubiquitination
Protein Ubiquitination
Histone H2B Ubiquitination
Response To Peptide Hormone
Negative Regulation Of MRNA Polyadenylation
Positive Regulation Of Proteasomal Protein Catabolic Process
Positive Regulation Of Protein Polyubiquitination
Positive Regulation Of Histone H2B Ubiquitination
Pathways
Eukaryotic Translation Elongation
E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS
Schizophrenia (
31268507
)
Immunoglobulin light chain (AL) amyloidosis (
28025584
)
Interacting Genes
41 interacting genes:
ABTB1
ALX1
APP
ARHGAP21
ASCC2
ATG7
CAMSAP2
CD48
CDK1
CDK9
CRMP1
CSNK2A1
CTBP1
CTBP2
ECH1
EEF1G
EPRS1
ERP27
FKBP6
FOS
FRA10AC1
GARS1
HEXD
HSF1
KARS1
KTN1
MAP1B
NR2F1
POT1
PRKCA
RELA
RNF40
RPS6KA1
SIAH1
SIAH2
SQSTM1
TERF1
TINF2
TPT1
UBE2A
VARS1
26 interacting genes:
AMOTL2
ATM
CCDC146
CDC73
DISC1
DUSP29
EEF1D
ITSN1
KIF11
MEOX2
MSL1
MTNR1B
NCBP1
NINL
RB1
RNF20
SFR1
TRIM51
UBE2A
UBE2B
UBE2D2
UBE2E1
UBE2I
UBE2L6
ZCCHC12
ZNF451
Entrez ID
1936
9810
HPRD ID
00560
07411
Ensembl ID
ENSG00000104529
ENSG00000103549
Uniprot IDs
B2RAR6
D3DWK1
P29692
A8K6K1
O75150
PDB IDs
2MVM
2MVN
2N51
5JPO
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Intersection)
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