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TRIM27 and KIFC3
Data Source:
BioGRID
(two hybrid)
TRIM27
KIFC3
Description
tripartite motif containing 27
kinesin family member C3
Image
No pdb structure
GO Annotations
Cellular Component
Fibrillar Center
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Endosome
Early Endosome
Cytosol
PML Body
Retromer Complex
Nuclear Membrane
Golgi Apparatus
Centrosome
Kinesin Complex
Microtubule
Zonula Adherens
Cytoplasmic Vesicle Membrane
Extracellular Exosome
Molecular Function
Nucleic Acid Binding
DNA Binding
Transcription Coactivator Activity
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Protein Kinase Binding
Identical Protein Binding
Protein Homodimerization Activity
Metal Ion Binding
Ubiquitin Protein Ligase Activity
Microtubule Motor Activity
Protein Binding
ATP Binding
Microtubule Binding
ATP-dependent Microtubule Motor Activity, Minus-end-directed
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Protein Polyubiquitination
Negative Regulation Of Adaptive Immune Response
Negative Regulation Of Protein Kinase Activity
Spermatogenesis
Regulation Of Gene Expression
Positive Regulation Of Autophagy
Protein Ubiquitination
Interferon-gamma Production
Negative Regulation Of Interleukin-2 Production
Negative Regulation Of Tumor Necrosis Factor Production
Regulation Of Protein Localization
Negative Regulation Of Viral Transcription
Arp2/3 Complex-mediated Actin Nucleation
Retrograde Transport, Endosome To Golgi
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Innate Immune Response
Negative Regulation Of Gene Expression, Epigenetic
Positive Regulation Of Transcription, DNA-templated
Regulation Of Viral Entry Into Host Cell
Positive Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of NF-kappaB Transcription Factor Activity
Protein K63-linked Ubiquitination
Negative Regulation Of Calcium Ion Import
Microtubule-based Movement
Golgi Organization
Visual Perception
Zonula Adherens Maintenance
Epithelial Cell-cell Adhesion
Pathways
SUMOylation of ubiquitinylation proteins
Regulation of PTEN stability and activity
Suppression of apoptosis
Drugs
Diseases
GWAS
Alopecia areata (
25608926
)
Asthma (
32296059
31619474
29273806
)
Asthma and major depressive disorder (
31619474
)
Autism spectrum disorder or schizophrenia (
28540026
)
Blood protein levels (
28240269
)
Body size at age 10 (
32376654
)
Brain morphology (MOSTest) (
32665545
)
Childhood and early adolescence aggressive behavior (
26087016
)
Daytime sleep phenotypes (
27126917
)
Estimated glomerular filtration rate in diabetes (
31451708
)
Experiencing mood swings (
29500382
)
Feeling miserable (
29500382
)
Fish- and plant-related diet (
32066663
)
General risk tolerance (MTAG) (
30643258
)
Hand grip strength (
29691431
)
Heel bone mineral density (
30598549
)
Hemoglobin levels (
32327693
)
Lung cancer in ever smokers (
28604730
)
Neurociticism (
29500382
)
Platelet aggregation (
20526338
)
Pre-treatment viral load in HIV-1 infection (
31219150
)
Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) (
26651848
)
Schizophrenia (
30285260
)
Social communication problems (
24047820
)
Subcortical volume (MOSTest) (
32665545
)
Triglyceride levels (
32203549
)
Interacting Genes
354 interacting genes:
ABCA1
ABCF3
ABHD17A
ACSF3
AEN
AMMECR1
AMOTL2
AP1M1
ARHGEF3
ARHGEF5
ARID5A
ARIH2
ARMC7
ARNT2
ARPIN
ATPAF2
ATXN7
AXIN1
BABAM1
BAG1
BAG3
BAG5
BEGAIN
BEX2
BMI1
BMP7
BYSL
C1orf109
CAPN7
CARD10
CATSPER1
CBX8
CCDC102B
CCDC185
CCDC187
CCDC198
CCDC87
CCDC92
CCHCR1
CDC20B
CDC23
CDC7
CDK18
CDKL3
CFAP206
CHCHD3
CHD4
CHUK
CKS1B
CLK2
CNNM3
COX5B
CPNE2
CPNE7
CREB5
CSRP2
CWF19L2
DBF4B
DCX
DDX6
DGCR6
DMRT3
DNMT1
DTNB
DTNBP1
EHHADH
EID1
EIF3D
EIF3E
EIF4A3
EIF4E
EIF4E2
ENKD1
EPC1
ERCC3
EXOC8
FAM110A
FAM126A
FAM126B
FAM161A
FAM193B
FAM214A
FAM214B
FAM83A
FAM90A1
FANCM
FARS2
FASTKD5
FBF1
FBXL19
FBXW5
FHL3
FNDC11
FOXB1
FOXC2
FXYD6
GADD45GIP1
GAS2L2
GATAD2B
GCC2-AS1
GEM
GFAP
GFI1B
GFM2
GLYCTK
GNE
GNPDA2
GPANK1
GPKOW
GRB14
GRB2
GSE1
GTF2F1
HAPLN2
HAUS1
HCK
HDAC1
HDAC4
HGS
HIP1R
HNRNPLL
HOXB5
HOXB9
HOXC8
HR
IGFN1
IKBKB
IKBKE
IL16
ILF2
ILK
INO80B
INPP5J
IP6K3
IQCE
IQCN
IQUB
JOSD1
KANSL1
KAT14
KAT5
KCTD15
KCTD9
KIF1A
KIF9
KIFC3
KRT3
KRT75
KRT76
LAGE3
LASP1
LENG1
LGALS14
LINC00526
LINGO1
LMNB2
LMO1
LMO4
LNX1
LONRF1
MAD2L2
MAGEA11
MAGED4B
MAGEF1
MAGOHB
MAPKBP1
MAT2B
MBD4
MCM7
MCOLN1
MDM2
MED21
MEMO1
MIA3
MID2
MOS
MRPL40
MSRB1
MTMR6
MVP
MYO15B
NCK2
NCOA1
NDE1
NDEL1
NEBL
NEDD9
NEIL2
NEK6
NELFE
NIF3L1
NME7
NOTCH2NLA
NR1D2
NTAQ1
NUDT21
OAS1
OTUB2
P2RX7
PIAS1
PIAS2
PIAS3
PIAS4
PIBF1
PIMREG
PIN1
PKN1
PLEKHN1
PML
POLE2
POLR1C
POLR3C
POM121
PPID
PPL
PPP1R18
PRAM1
PRKAA1
PRPF18
PRPF31
PRR35
PSMA1
PSMB1
PSMB3
PTPMT1
PTPN23
PUS7L
QARS1
RAB29
RAMAC
RB1
RBM23
RBM41
RBX1
RCOR3
REL
RHPN1
RIBC1
RIN1
RNF213
RNF25
RNF6
RSPH14
RXRB
SCNM1
SDCBP
SH2D4A
SIAH1
SIRPA
SLC15A3
SMARCB1
SMARCD1
SMG9
SNRPA
SNRPB2
SORBS3
SPATA2
SPATC1L
SRSF2
STAMBPL1
STK16
STK25
STK26
SYNGAP1
SYT17
SYT6
TACO1
TBC1D22B
TBK1
TCEA2
TCEANC
TCHP
TEAD4
TEX33
THOC1
TLE5
TMSB4X
TMSB4XP6
TNS4
TP53
TPM3
TPRKB
TRAF4
TRAF5
TRIM11
TRIM21
TRIM23
TRIM29
TRIM31
TRIM32
TRIM42
TRIM43
TRIM50
TRIM55
TRIM9
TSGA10IP
TSHZ3
TTLL10
TUBGCP4
TUFT1
TXNDC9
UBASH3A
UBE2A
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E2
UBE2E3
UBE2H
UBE2I
UBE2J1
UBE2K
UBE2L6
UBE2N
UBE2O
UBE2T
UBE2U
UBE2W
UBE2Z
UBL5
UCHL3
UCHL5
UHRF2
USE1
USP2
UTP14C
UTP23
VEZF1
VPS25
VPS28
VPS9D1
WT1-AS
XPA
YJU2
ZBTB16
ZC2HC1C
ZFC3H1
ZFHX3
ZFYVE21
ZGPAT
ZMYND19
ZNF250
ZNF384
ZNF414
ZNF417
ZNF446
ZNF572
ZNF580
ZNF581
ZNF587
ZNF688
ZNF79
209 interacting genes:
ABI2
ABI3
ANKRD23
ANXA13
APP
APPL2
ARNT2
ATF2
AXIN2
BARD1
BCL6
BEGAIN
BFSP1
BYSL
C1orf109
C2CD6
CARD9
CBFA2T2
CBX8
CBY2
CCDC102B
CCDC136
CCDC146
CCDC187
CCDC198
CCDC28A
CCDC33
CCHCR1
CCND3
CDC37
CDK18
CDKN1A
CDR2
CEP55
CEP57L1
CLIP4
COG3
COG7
CREB5
CWF19L2
CYTH4
DCTN2
DCX
DEUP1
DISC1
DTNBP1
EIF3D
ENKD1
ESRRG
EXOC5
EXOC7
EXOC8
FAM124A
FAM161A
FAM90A1
FANCL
FBXO7
FCHSD2
FEM1A
FLYWCH1
FOSL1
GADD45GIP1
GEM
GIGYF1
GMCL1
GOLGA1
GOLGA2
GORASP2
HAUS1
HMG20A
HOMEZ
HSBP1
HSF2BP
ICA1L
IGFN1
IHO1
IKZF3
IL16
IQUB
ITGB3BP
KANK2
KANSL1
KDM1A
KIAA0753
KRT14
KRT15
KRT16
KRT18
KRT19
KRT26
KRT3
KRT31
KRT32
KRT35
KRT38
KRT40
KRT5
KRT6A
KRT6B
KRT6C
KRT75
KRT76
KRTAP19-5
KRTAP19-6
LBX1
LENG1
LIN37
LNX1
LZTS1
LZTS2
MBD3L1
MCC
MCM7
MED4
MFAP1
MID2
MKRN3
MOS
MRFAP1
MTUS2
MYO15B
NAB2
NDC80
NDEL1
NEBL
NECAB2
NEDD4
NEDD4L
NEFL
NSMF
NUP62
PFDN6
PHC2
PIAS2
PIBF1
PIN1
PNMA5
PPP1R13B
PRDM6
PRKAA2
PRPF18
PRPF31
PRPH
PSMB1
RABIF
RAD51D
RAD54L2
RBM41
RSPH14
RUNX1T1
SCEL
SCNM1
SCOC
SHISA6
SIAH1
SMARCE1
SNAP29
SORBS3
SOX30
SOX5
SPATA2
SPATC1L
SSX2IP
STMN3
STX11
STX1A
SVIL
SYCE1
SYCE2
SYT6
SYTL4
TASOR2
TBC1D22B
TCEANC
TFIP11
TLE5
TNIP1
TNNI1
TPM3
TRAF2
TRIM14
TRIM23
TRIM27
TRIM41
TRIM54
TSG101
TSGA10IP
TSR2
USH1G
USP2
VIM
VPS52
WASF3
ZBED1
ZBTB16
ZBTB8A
ZGPAT
ZNF180
ZNF20
ZNF250
ZNF417
ZNF446
ZNF572
ZNF655
ZNF688
ZNF774
ZNF785
ZNF835
ZRANB1
Entrez ID
5987
3801
HPRD ID
15996
05171
Ensembl ID
ENSG00000204713
ENSG00000140859
Uniprot IDs
A0A1U9X8R9
P14373
B7Z5U4
B7Z808
B7Z896
F5H3M2
Q9BVG8
PDB IDs
5WDE
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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