Wiki-Pi
About
Search
Browse
People
Updates
Search
KIFC3 and NEDD4
Data Source:
BioGRID
(pull down)
KIFC3
NEDD4
Description
kinesin family member C3
NEDD4 E3 ubiquitin protein ligase
Image
GO Annotations
Cellular Component
Golgi Apparatus
Centrosome
Kinesin Complex
Microtubule
Zonula Adherens
Cytoplasmic Vesicle Membrane
Extracellular Exosome
Ubiquitin Ligase Complex
Chromatin
Cytoplasm
Golgi Apparatus
Cytosol
Plasma Membrane
Cell Cortex
Apicolateral Plasma Membrane
Protein-containing Complex
Dendritic Spine
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Molecular Function
Microtubule Motor Activity
Protein Binding
ATP Binding
Microtubule Binding
ATP-dependent Microtubule Motor Activity, Minus-end-directed
Protein Binding
Sodium Channel Inhibitor Activity
Enzyme Binding
Protein Domain Specific Binding
Beta-2 Adrenergic Receptor Binding
Ubiquitin Binding
Phosphoserine Residue Binding
Phosphothreonine Residue Binding
Ubiquitin Protein Ligase Activity
RNA Polymerase Binding
Proline-rich Region Binding
Biological Process
Microtubule-based Movement
Golgi Organization
Visual Perception
Zonula Adherens Maintenance
Epithelial Cell-cell Adhesion
Protein Polyubiquitination
Ubiquitin-dependent Protein Catabolic Process
Protein Targeting To Lysosome
Lysosomal Transport
Neuromuscular Junction Development
Negative Regulation Of Sodium Ion Transport
Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage
Positive Regulation Of Phosphatidylinositol 3-kinase Signaling
Regulation Of Macroautophagy
Protein Ubiquitination
Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway
Neuron Projection Development
Receptor Internalization
Receptor Catabolic Process
Cellular Response To UV
Regulation Of Ion Transmembrane Transport
Regulation Of Membrane Potential
Glucocorticoid Receptor Signaling Pathway
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Development Involved In Symbiotic Interaction
Positive Regulation Of Protein Catabolic Process
Viral Budding
Positive Regulation Of Nucleocytoplasmic Transport
Regulation Of Dendrite Morphogenesis
Regulation Of Synapse Organization
Progesterone Receptor Signaling Pathway
Response To Calcium Ion
Protein K63-linked Ubiquitination
Regulation Of Potassium Ion Transmembrane Transporter Activity
Negative Regulation Of Sodium Ion Transmembrane Transporter Activity
Pathways
ISG15 antiviral mechanism
Downregulation of ERBB4 signaling
Regulation of PTEN localization
Regulation of PTEN stability and activity
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Brain connectivity (
23471985
)
Chronic lymphocytic leukemia (
28165464
24292274
)
Dupuytren's disease (
28886342
)
Hip circumference adjusted for BMI (
28552196
)
Intraocular pressure (
29617998
)
Joint mobility (Beighton score) (
27182965
)
Keloid (
20711176
)
Refractive error (
32231278
)
Stroke (
29531354
)
Interacting Genes
209 interacting genes:
ABI2
ABI3
ANKRD23
ANXA13
APP
APPL2
ARNT2
ATF2
AXIN2
BARD1
BCL6
BEGAIN
BFSP1
BYSL
C1orf109
C2CD6
CARD9
CBFA2T2
CBX8
CBY2
CCDC102B
CCDC136
CCDC146
CCDC187
CCDC198
CCDC28A
CCDC33
CCHCR1
CCND3
CDC37
CDK18
CDKN1A
CDR2
CEP55
CEP57L1
CLIP4
COG3
COG7
CREB5
CWF19L2
CYTH4
DCTN2
DCX
DEUP1
DISC1
DTNBP1
EIF3D
ENKD1
ESRRG
EXOC5
EXOC7
EXOC8
FAM124A
FAM161A
FAM90A1
FANCL
FBXO7
FCHSD2
FEM1A
FLYWCH1
FOSL1
GADD45GIP1
GEM
GIGYF1
GMCL1
GOLGA1
GOLGA2
GORASP2
HAUS1
HMG20A
HOMEZ
HSBP1
HSF2BP
ICA1L
IGFN1
IHO1
IKZF3
IL16
IQUB
ITGB3BP
KANK2
KANSL1
KDM1A
KIAA0753
KRT14
KRT15
KRT16
KRT18
KRT19
KRT26
KRT3
KRT31
KRT32
KRT35
KRT38
KRT40
KRT5
KRT6A
KRT6B
KRT6C
KRT75
KRT76
KRTAP19-5
KRTAP19-6
LBX1
LENG1
LIN37
LNX1
LZTS1
LZTS2
MBD3L1
MCC
MCM7
MED4
MFAP1
MID2
MKRN3
MOS
MRFAP1
MTUS2
MYO15B
NAB2
NDC80
NDEL1
NEBL
NECAB2
NEDD4
NEDD4L
NEFL
NSMF
NUP62
PFDN6
PHC2
PIAS2
PIBF1
PIN1
PNMA5
PPP1R13B
PRDM6
PRKAA2
PRPF18
PRPF31
PRPH
PSMB1
RABIF
RAD51D
RAD54L2
RBM41
RSPH14
RUNX1T1
SCEL
SCNM1
SCOC
SHISA6
SIAH1
SMARCE1
SNAP29
SORBS3
SOX30
SOX5
SPATA2
SPATC1L
SSX2IP
STMN3
STX11
STX1A
SVIL
SYCE1
SYCE2
SYT6
SYTL4
TASOR2
TBC1D22B
TCEANC
TFIP11
TLE5
TNIP1
TNNI1
TPM3
TRAF2
TRIM14
TRIM23
TRIM27
TRIM41
TRIM54
TSG101
TSGA10IP
TSR2
USH1G
USP2
VIM
VPS52
WASF3
ZBED1
ZBTB16
ZBTB8A
ZGPAT
ZNF180
ZNF20
ZNF250
ZNF417
ZNF446
ZNF572
ZNF655
ZNF688
ZNF774
ZNF785
ZNF835
ZRANB1
238 interacting genes:
ABCB1
ABL1
ABL2
ADRB2
AKT3
AMOT
AMOTL1
AMPD2
ANKRD13D
ANXA13
AP1G2
ARID1A
ASPSCR1
AURKC
BAIAP2
BMPR1A
BRCA2
CAD
CALCOCO1
CAMK1D
CAMK4
CAMKK2
CASP1
CASP3
CASP6
CASP7
CBLB
CCNH
CDC25C
CDK5
CDK5R1
CLIC2
CLK3
CPSF1
CPSF6
CUEDC1
DAZAP2
DCUN1D1
DDX3X
DDX54
DHX30
DIAPH1
DVL1
DYRK4
EBAG9
EGFR
EPHA5
EPRS1
EPS15
ERBB3
ERBB4
ERMN
ERRFI1
FES
FGF12
FGF21
FGFR1
FGFR2
FKBP3
FLT1
FLT4
FYN
GABARAP
GABARAPL1
GABARAPL2
GBA
GFUS
GRB10
GRIN2A
GRK4
GRK7
H3-3A
HGS
HMCES
HNRNPK
HNRNPL
HNRNPU
HNRNPUL1
IFITM3
IGF1R
IRS1
IRS2
JHY
JUN
KCNAB1
KCNAB2
KCNJ16
KIFC3
LAPTM5
LATS1
LINC01198
LITAF
LUC7L2
MAP1LC3A
MAP1LC3B
MAP1LC3C
MAP3K2
MAP3K3
MAP3K5
MAP4K5
MAPKAPK3
MARK2
MARK4
MLANA
MOB3A
MRPL19
MTMR4
MYCN
MYO15B
N4BP2
N4BP3
NDFIP1
NDFIP2
NFE2
NHP2
NSRP1
NUDT21
NUMB
PARP16
PAX7
PDGFRB
PIP5K1A
PIP5K1C
PKN2
PLK1
PLK2
PMEPA1
POLR1C
POLR2A
POLR2B
POLR2C
POLR2E
POLR2M
POLR3A
PRKG2
PRKX
PRPF8
PRR16
PRRG1
PRRG2
PSMD4
PYM1
RAC1
RAD51AP1
RAF1
RANBP10
RAP2A
RAPGEF2
RAPGEF6
RASGEF1A
RASL11B
RBCK1
RET
RFT1
RNF11
RNF7
RPAP2
RPAP3
RPL18A
RPS3A
RPS6KA3
RPS6KA4
RPS6KB1
RUNX1
RUVBL1
SAAL1
SAMSN1
SAV1
SCAMP3
SCN5A
SCNN1A
SCNN1B
SCNN1G
SEPTIN9
SERTAD1
SFTPC
SGK1
SGK2
SH3KBP1
SHISA6
SHTN1
SIVA1
SLC23A2
SLC6A3
SMAD1
SMAD3
SMAD5
SMARCC1
SMO
SNCA
SP140L
SPANXN3
SPRY2
SRC
SRMS
SRSF7
STK24
STK25
STK26
STK31
STK4
SULF1
SYK
SYT1
TAF1B
TBC1D7
TBK1
TCEANC
TCP11L1
TEAD2
THOC1
THRAP3
TNIK
TOM1
TOM1L2
TP53BP2
TP73
TRIM44
TRIM52
TRPV6
TTYH2
UBAP2L
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2E1
UBE2L3
UBE2M
UBOX5
URI1
VDAC2
VDAC3
WBP1
WBP2
WEE1
YES1
YOD1
Entrez ID
3801
4734
HPRD ID
05171
03786
Ensembl ID
ENSG00000140859
ENSG00000069869
Uniprot IDs
B7Z5U4
B7Z808
B7Z896
F5H3M2
Q9BVG8
P46934
PDB IDs
5WDE
2KPZ
2KQ0
2M3O
2XBB
2XBF
3B7Y
4BBN
4BE8
4N7F
4N7H
5AHT
5C7J
5C91
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?