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KIFC3 and PRKAA2
Data Source:
BioGRID
(two hybrid, two hybrid)
KIFC3
PRKAA2
Description
kinesin family member C3
protein kinase AMP-activated catalytic subunit alpha 2
Image
GO Annotations
Cellular Component
Golgi Apparatus
Centrosome
Kinesin Complex
Microtubule
Zonula Adherens
Cytoplasmic Vesicle Membrane
Extracellular Exosome
Nucleus
Nucleoplasm
Cytoplasm
Golgi Apparatus
Cytosol
Cytoplasmic Stress Granule
Nuclear Speck
Axon
Dendrite
Neuronal Cell Body
Molecular Function
Microtubule Motor Activity
Protein Binding
ATP Binding
Microtubule Binding
ATP-dependent Microtubule Motor Activity, Minus-end-directed
Chromatin Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
AMP-activated Protein Kinase Activity
Protein Serine/threonine/tyrosine Kinase Activity
Protein Binding
ATP Binding
Histone Serine Kinase Activity
Metal Ion Binding
[hydroxymethylglutaryl-CoA Reductase (NADPH)] Kinase Activity
[acetyl-CoA Carboxylase] Kinase Activity
Protein Serine Kinase Activity
Protein Threonine Kinase Activity
Biological Process
Microtubule-based Movement
Golgi Organization
Visual Perception
Zonula Adherens Maintenance
Epithelial Cell-cell Adhesion
Protein Phosphorylation
Fatty Acid Biosynthetic Process
Cholesterol Biosynthetic Process
Carnitine Shuttle
Cell Cycle Arrest
Signal Transduction
Lipid Biosynthetic Process
Positive Regulation Of Autophagy
Negative Regulation Of Gene Expression
Response To Muscle Activity
Wnt Signaling Pathway
Macroautophagy
Positive Regulation Of Macroautophagy
Regulation Of Macroautophagy
Cellular Response To Nutrient Levels
Negative Regulation Of TOR Signaling
Cellular Response To Oxidative Stress
Histone-serine Phosphorylation
Intracellular Signal Transduction
Cellular Response To Drug
Cellular Response To Glucose Starvation
Regulation Of Fatty Acid Biosynthetic Process
Glucose Homeostasis
Regulation Of Circadian Rhythm
Negative Regulation Of Apoptotic Process
Positive Regulation Of Glycolytic Process
Rhythmic Process
Fatty Acid Homeostasis
Regulation Of Stress Granule Assembly
Regulation Of Microtubule Cytoskeleton Organization
Cellular Response To Calcium Ion
Cellular Response To Glucose Stimulus
Cellular Response To Prostaglandin E Stimulus
Energy Homeostasis
Regulation Of Signal Transduction By P53 Class Mediator
Positive Regulation Of Cellular Protein Localization
Negative Regulation Of Tubulin Deacetylation
Positive Regulation Of Peptidyl-lysine Acetylation
Pathways
Translocation of SLC2A4 (GLUT4) to the plasma membrane
Macroautophagy
AMPK inhibits chREBP transcriptional activation activity
AMPK inhibits chREBP transcriptional activation activity
Carnitine metabolism
Activation of PPARGC1A (PGC-1alpha) by phosphorylation
Energy dependent regulation of mTOR by LKB1-AMPK
TP53 Regulates Metabolic Genes
Regulation of TP53 Activity through Phosphorylation
Lipophagy
Activation of AMPK downstream of NMDARs
Drugs
Adenosine phosphate
Acetylsalicylic acid
Fostamatinib
Diseases
GWAS
Lymphocyte counts (
22286170
)
Interacting Genes
209 interacting genes:
ABI2
ABI3
ANKRD23
ANXA13
APP
APPL2
ARNT2
ATF2
AXIN2
BARD1
BCL6
BEGAIN
BFSP1
BYSL
C1orf109
C2CD6
CARD9
CBFA2T2
CBX8
CBY2
CCDC102B
CCDC136
CCDC146
CCDC187
CCDC198
CCDC28A
CCDC33
CCHCR1
CCND3
CDC37
CDK18
CDKN1A
CDR2
CEP55
CEP57L1
CLIP4
COG3
COG7
CREB5
CWF19L2
CYTH4
DCTN2
DCX
DEUP1
DISC1
DTNBP1
EIF3D
ENKD1
ESRRG
EXOC5
EXOC7
EXOC8
FAM124A
FAM161A
FAM90A1
FANCL
FBXO7
FCHSD2
FEM1A
FLYWCH1
FOSL1
GADD45GIP1
GEM
GIGYF1
GMCL1
GOLGA1
GOLGA2
GORASP2
HAUS1
HMG20A
HOMEZ
HSBP1
HSF2BP
ICA1L
IGFN1
IHO1
IKZF3
IL16
IQUB
ITGB3BP
KANK2
KANSL1
KDM1A
KIAA0753
KRT14
KRT15
KRT16
KRT18
KRT19
KRT26
KRT3
KRT31
KRT32
KRT35
KRT38
KRT40
KRT5
KRT6A
KRT6B
KRT6C
KRT75
KRT76
KRTAP19-5
KRTAP19-6
LBX1
LENG1
LIN37
LNX1
LZTS1
LZTS2
MBD3L1
MCC
MCM7
MED4
MFAP1
MID2
MKRN3
MOS
MRFAP1
MTUS2
MYO15B
NAB2
NDC80
NDEL1
NEBL
NECAB2
NEDD4
NEDD4L
NEFL
NSMF
NUP62
PFDN6
PHC2
PIAS2
PIBF1
PIN1
PNMA5
PPP1R13B
PRDM6
PRKAA2
PRPF18
PRPF31
PRPH
PSMB1
RABIF
RAD51D
RAD54L2
RBM41
RSPH14
RUNX1T1
SCEL
SCNM1
SCOC
SHISA6
SIAH1
SMARCE1
SNAP29
SORBS3
SOX30
SOX5
SPATA2
SPATC1L
SSX2IP
STMN3
STX11
STX1A
SVIL
SYCE1
SYCE2
SYT6
SYTL4
TASOR2
TBC1D22B
TCEANC
TFIP11
TLE5
TNIP1
TNNI1
TPM3
TRAF2
TRIM14
TRIM23
TRIM27
TRIM41
TRIM54
TSG101
TSGA10IP
TSR2
USH1G
USP2
VIM
VPS52
WASF3
ZBED1
ZBTB16
ZBTB8A
ZGPAT
ZNF180
ZNF20
ZNF250
ZNF417
ZNF446
ZNF572
ZNF655
ZNF688
ZNF774
ZNF785
ZNF835
ZRANB1
122 interacting genes:
ABI1
ABI2
ACACA
ACACB
AIMP2
AKAP8L
AMOT
AMOTL2
ANAPC11
APPBP2
ARRDC3
AVPI1
C19orf47
CALCOCO1
CALCOCO2
CCDC172
CCDC33
CCNB1IP1
CDC42EP1
CDR2
CDX4
CPSF7
CTAG2
CYSRT1
DNAAF6
DNM2
DNMT1
DVL3
EEF2K
EMILIN1
EPM2A
EPN2
FNDC3B
FOS
GIGYF1
GLI1
GOLGA2
GOLGA6A
GRAP2
HAT1
HMBOX1
HNF4A
HOMEZ
IKZF1
IKZF3
KCTD1
KCTD9
KIAA1328
KIF16B
KIF24
KIFC3
KRT16
KRT31
KRTAP1-3
KRTAP10-3
KRTAP10-9
L3MBTL3
LCN2
LEP
LZTS2
MKRN3
MORN3
MRFAP1
MTUS2
MYCL
MYOZ1
NAB2
NECAB2
NONO
NOTCH2NLA
NRAP
NRBF2
NUTM1
PBXIP1
PFKFB2
PLEKHN1
PPP1R32
PRDM6
PRKAB1
PRKAG1
PRKAR1B
PRKN
PRPH
RASAL3
RBBP7
RBPMS
REL
RFX6
RPTOR
SERTAD3
SKIV2L
SLA2
SNW1
SOHLH1
SPRY1
STAC2
STK11
TCF4
TFAP2A
TIFA
TLE5
TMOD1
TRIP13
TRIP6
TSC22D4
UBE2I
USH1C
USH1G
USHBP1
USP10
VPS28
VPS37B
VPS52
WASHC1
WWP1
WWP2
YPEL3
ZBTB8A
ZMYND12
ZNF212
ZNF397
ZSCAN23
Entrez ID
3801
5563
HPRD ID
05171
02735
Ensembl ID
ENSG00000140859
ENSG00000162409
Uniprot IDs
B7Z5U4
B7Z808
B7Z896
F5H3M2
Q9BVG8
P54646
PDB IDs
5WDE
2H6D
2LTU
2YZA
3AQV
4CFE
4CFF
4ZHX
5EZV
5ISO
6B1U
6B2E
6BX6
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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