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ACTA1 and TPM2
Data Source:
BioGRID
(pull down)
ACTA1
TPM2
Description
actin alpha 1, skeletal muscle
tropomyosin 2
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Stress Fiber
Extracellular Space
Cytosol
Striated Muscle Thin Filament
Dynactin Complex
Actin Filament
Actin Cytoskeleton
Sarcomere
Lamellipodium
Filopodium
Cell Body
Extracellular Exosome
Blood Microparticle
Cytosol
Muscle Thin Filament Tropomyosin
Actin Filament
Actin Cytoskeleton
Molecular Function
Structural Constituent Of Cytoskeleton
Protein Binding
ATP Binding
Myosin Binding
ADP Binding
Actin Binding
Structural Constituent Of Muscle
Identical Protein Binding
Protein Homodimerization Activity
Protein Heterodimerization Activity
Actin Filament Binding
Biological Process
Muscle Contraction
Response To Mechanical Stimulus
Response To Extracellular Stimulus
Response To Lithium Ion
Positive Regulation Of Gene Expression
Muscle Filament Sliding
Skeletal Muscle Thin Filament Assembly
Skeletal Muscle Fiber Adaptation
Response To Steroid Hormone
Skeletal Muscle Fiber Development
Cellular Response To Organonitrogen Compound
Mesenchyme Migration
Muscle Contraction
Actin Filament Organization
Muscle Filament Sliding
Regulation Of ATPase Activity
Pathways
Striated Muscle Contraction
Striated Muscle Contraction
Smooth Muscle Contraction
Drugs
Latrunculin A
Sucrose
Ulapualide A
Kabiramide C
Jaspisamide A
Tmr
1-Methylhistidine
Phosphoaminophosphonic Acid-Adenylate Ester
Aplyronine A
Reidispongiolide A
Reidispongiolide C
Sphinxolide B
Latrunculin B
Diseases
Congenital fiber type disproportion (CFTD)
Cap myopathy
Nemaline myopathy
Cap myopathy
Distal arthrogryposis (DA)
Nemaline myopathy
GWAS
Immature fraction of reticulocytes (
32888494
)
Platelet count (
32888494
)
White blood cell count (
32888494
)
Interacting Genes
114 interacting genes:
ABL1
ABRA
ACTR10
ACTR1B
ADSS2
AFAP1
AIF1
AJUBA
AMOT
ANXA2
BIN1
CCIN
CCT2
CCT4
CCT5
CFL1
CLIC5
CNN1
CORO2B
COTL1
CTNND1
CTTN
CYFIP1
CYTH1
DHX9
DLG1
DMD
DNASE1
DNMBP
DTNA
DUX4L9
EGFR
EPB41
EPB41L2
EPS8
FGD4
FHOD1
FSCN1
GAS2
GAS7
GC
GSN
HCLS1
HDAC4
HIP1R
HSPB2
HTRA2
IQGAP1
ITGA2
ITPKA
KIF23
KLHL20
LASP1
MACF1
MAP1A
MAPT
MIB2
MINPP1
MYL1
MYLK
MYO10
MYO6
MYO7A
MYO9B
NEXN
NR3C2
NRAP
PAK1
PARVA
PCYT1B
PFDN1
PFN1
PHACTR1
PLD1
PPP1R9B
PRKCA
PRKCD
PRKCE
RAC1
RNF167
RPS6KB1
S100A1
S100A4
SCIN
SMTN
SNCA
SORBS1
SPRR1A
SPTA1
SPTAN1
SPTBN2
TAGLN
TJP1
TLN1
TMSB4X
TMSB4Y
TNNI1
TNNI3
TNNI3K
TP53
TPM2
TPM3
TRIM55
TRIM63
TTN
UBC
USP25
USP6NL
UTRN
VASP
VAV1
VCL
VIL1
XIRP1
22 interacting genes:
ABI2
ACTA1
ACTB
FARS2
GRK2
JUN
MAST2
MESD
MRFAP1
NEB
PDLIM7
PIK3CG
RRAD
S100A2
S100A4
SKIL
SNAPIN
TFPT
TPM1
ZNF229
ZNF620
ZNF785
Entrez ID
58
7169
HPRD ID
00030
11768
Ensembl ID
ENSG00000143632
ENSG00000198467
Uniprot IDs
P68133
A7XZE4
P07951
Q5TCU3
V9HW25
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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