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ACTA1 and CYFIP1
Data Source:
HPRD
(in vitro)
ACTA1
CYFIP1
Description
actin alpha 1, skeletal muscle
cytoplasmic FMR1 interacting protein 1
Image
No pdb structure
GO Annotations
Cellular Component
Stress Fiber
Extracellular Space
Cytosol
Striated Muscle Thin Filament
Dynactin Complex
Actin Filament
Actin Cytoskeleton
Sarcomere
Lamellipodium
Filopodium
Cell Body
Extracellular Exosome
Blood Microparticle
Ruffle
Extracellular Region
Cytosol
MRNA Cap Binding Complex
Focal Adhesion
Lamellipodium
SCAR Complex
Filopodium Tip
Secretory Granule Lumen
Specific Granule Lumen
Neuron Projection
Neuronal Cell Body
Terminal Bouton
Dendritic Spine
Dendritic Growth Cone
Axonal Growth Cone
Synapse
Perinuclear Region Of Cytoplasm
Excitatory Synapse
Extracellular Exosome
Central Region Of Growth Cone
Peripheral Region Of Growth Cone
Tertiary Granule Lumen
Molecular Function
Structural Constituent Of Cytoskeleton
Protein Binding
ATP Binding
Myosin Binding
ADP Binding
RNA 7-methylguanosine Cap Binding
Protein Binding
Small GTPase Binding
Translation Regulator Activity
Actin Filament Binding
Biological Process
Muscle Contraction
Response To Mechanical Stimulus
Response To Extracellular Stimulus
Response To Lithium Ion
Positive Regulation Of Gene Expression
Muscle Filament Sliding
Skeletal Muscle Thin Filament Assembly
Skeletal Muscle Fiber Adaptation
Response To Steroid Hormone
Skeletal Muscle Fiber Development
Cellular Response To Organonitrogen Compound
Mesenchyme Migration
Cell Morphogenesis
Regulation Of Translation
Axon Guidance
Regulation Of Cell Shape
Positive Regulation Of Lamellipodium Assembly
Rac Protein Signal Transduction
Cell Projection Assembly
Lamellipodium Assembly
Ruffle Organization
Regulation Of Myelination
Cellular Response To Insulin Stimulus
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Neutrophil Degranulation
Positive Regulation Of Axon Extension
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Axon Extension
Cognition
Positive Regulation Of Neurotrophin TRK Receptor Signaling Pathway
Response To Electrical Stimulus
Dendrite Extension
Modification Of Synaptic Structure
Regulation Of Translation At Postsynapse, Modulating Synaptic Transmission
Positive Regulation Of Dendrite Development
Positive Regulation Of Ruffle Assembly
Negative Regulation Of Synaptic Vesicle Recycling
Regulation Of Modification Of Postsynaptic Actin Cytoskeleton
Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Pathways
Striated Muscle Contraction
Regulation of actin dynamics for phagocytic cup formation
Regulation of actin dynamics for phagocytic cup formation
VEGFA-VEGFR2 Pathway
RHO GTPases Activate WASPs and WAVEs
RHO GTPases Activate WASPs and WAVEs
Neutrophil degranulation
FCGR3A-mediated phagocytosis
FCGR3A-mediated phagocytosis
Drugs
Latrunculin A
Sucrose
Ulapualide A
Kabiramide C
Jaspisamide A
Tmr
1-Methylhistidine
Phosphoaminophosphonic Acid-Adenylate Ester
Aplyronine A
Reidispongiolide A
Reidispongiolide C
Sphinxolide B
Latrunculin B
Diseases
Congenital fiber type disproportion (CFTD)
Cap myopathy
Nemaline myopathy
GWAS
Heel bone mineral density (
30598549
)
Platelet distribution width (
32888494
)
Triglyceride levels x loop diuretics use interaction (
31806883
)
World class endurance athleticism (
32612638
)
Interacting Genes
114 interacting genes:
ABL1
ABRA
ACTR10
ACTR1B
ADSS2
AFAP1
AIF1
AJUBA
AMOT
ANXA2
BIN1
CCIN
CCT2
CCT4
CCT5
CFL1
CLIC5
CNN1
CORO2B
COTL1
CTNND1
CTTN
CYFIP1
CYTH1
DHX9
DLG1
DMD
DNASE1
DNMBP
DTNA
DUX4L9
EGFR
EPB41
EPB41L2
EPS8
FGD4
FHOD1
FSCN1
GAS2
GAS7
GC
GSN
HCLS1
HDAC4
HIP1R
HSPB2
HTRA2
IQGAP1
ITGA2
ITPKA
KIF23
KLHL20
LASP1
MACF1
MAP1A
MAPT
MIB2
MINPP1
MYL1
MYLK
MYO10
MYO6
MYO7A
MYO9B
NEXN
NR3C2
NRAP
PAK1
PARVA
PCYT1B
PFDN1
PFN1
PHACTR1
PLD1
PPP1R9B
PRKCA
PRKCD
PRKCE
RAC1
RNF167
RPS6KB1
S100A1
S100A4
SCIN
SMTN
SNCA
SORBS1
SPRR1A
SPTA1
SPTAN1
SPTBN2
TAGLN
TJP1
TLN1
TMSB4X
TMSB4Y
TNNI1
TNNI3
TNNI3K
TP53
TPM2
TPM3
TRIM55
TRIM63
TTN
UBC
USP25
USP6NL
UTRN
VASP
VAV1
VCL
VIL1
XIRP1
18 interacting genes:
ACTA1
APBB1
EFHC2
EFTUD2
FMR1
FXR2
GAS7
GNB1
MEOX1
MYO16
NYAP1
NYAP2
PPP1CC
PRPF40A
RAC1
RFX6
SCTR
TCERG1
Entrez ID
58
23191
HPRD ID
00030
05890
Ensembl ID
ENSG00000143632
ENSG00000273749
Uniprot IDs
P68133
Q7L576
PDB IDs
3P8C
4N78
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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