SCAF4 and WBP4

Data Source:
BioGRID (pull down)

		SCAF4	WBP4
Description		SR-related CTD associated factor 4	WW domain binding protein 4
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleus Nucleoplasm Nuclear Speck U2-type Precatalytic Spliceosome Precatalytic Spliceosome
	Molecular Function	RNA Binding Protein C-terminus Binding RNA Polymerase II C-terminal Domain Phosphoserine Binding	RNA Binding Protein Binding Zinc Ion Binding Proline-rich Region Binding
	Biological Process	MRNA Processing Negative Regulation Of Termination Of RNA Polymerase II Transcription, Poly(A)-coupled	MRNA Splicing, Via Spliceosome RNA Splicing MRNA Cis Splicing, Via Spliceosome
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Adverse response to drug ( 30420678) Apolipoprotein B levels ( 32203549) Joint damage progression in ACPA-negative rheumatoid arthritis ( 26077402) LDL cholesterol ( 30275531)	Crohn's disease ( 23266558) CSF tryptophan concentration in tuberculous meningitis ( 29395996) Intraocular pressure ( 29617998) Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444 31624269)
Interacting Genes		2 interacting genes: TP63 WBP4	54 interacting genes: ARGLU1 BUB3 CAPRIN1 CHERP CHTF8 CPSF6 CPSF7 DDX23 DDX3X DHX15 DHX38 DIAPH1 DNM2 EFTUD2 EWSR1 FAM50B FUS HLTF HNRNPK HNRNPU HTATSF1 ISY1 KHDRBS1 NONO PABPC1 PPIA PRPF3 PRPF4 PRPF40A PSPC1 SART1 SCAF4 SF1 SF3A1 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SNRNP200 SNRNP70 SNRPA SNRPB SNW1 TCERG1 TIA1 WAS WBP11 WDR83 WIPF1 XRCC6 ZC2HC1A ZNF207
Entrez ID		57466	11193
HPRD ID		11551	16086
Ensembl ID		ENSG00000156304	ENSG00000120688
Uniprot IDs		O95104	O75554
PDB IDs			2DK1 2JXW 5O9Z 6AHD
Enriched GO Terms of Interacting Partners?
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