TBC1D22B and LHX8

Data Source:
BioGRID (two hybrid)

		TBC1D22B	LHX8
Description		TBC1 domain family member 22B	LIM homeobox 8
Image			No pdb structure
GO Annotations	Cellular Component		Chromatin Female Germ Cell Nucleus Nucleus
	Molecular Function	GTPase Activator Activity Protein Binding 14-3-3 Protein Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Intracellular Protein Transport Activation Of GTPase Activity Regulation Of Cilium Assembly	Regulation Of Transcription By RNA Polymerase II Learning Or Memory Female Gonad Development Forebrain Neuron Development Neuron Differentiation Odontogenesis Of Dentin-containing Tooth
Pathways
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Blood glucose levels ( 31928498) Platelet count ( 27863252) Systolic blood pressure ( 31928498) Triglyceride levels ( 31928498)
Interacting Genes		58 interacting genes: AP1B1 ARHGEF9 BLZF1 CALCOCO2 CARD10 CCDC57 CCDC88B CDR2 CEP63 CEP70 COG6 DAPK1 DDIT4L DEUP1 EFHC2 EXOC8 FHL3 FXR1 FXR2 GFAP GOLGA2 HMG20A HOMER3 HOOK2 HSD17B14 IKZF3 KIFC3 KRT34 KRT40 LHX8 LIMS1 LRRK2 MFHAS1 MID2 MTUS2 PICK1 PLEKHG4 PNMA5 RBM10 RBM48 REL SIAH1 SLAIN1 SORBS3 SPATA2 TACC3 TEPSIN TEX11 TP53BP2 TRIM23 TRIM27 TRIM54 TRIP6 VPS52 ZFP90 ZNF438 ZNF76 ZSCAN4	27 interacting genes: ABI2 ATF2 ATF6B AXIN1 BANP CCHCR1 CRK CSNK2A1 EFS FIGLA FOSL2 FOXN1 GINS4 KLF3 KRT85 LDB1 LDB2 NEDD9 NUTM1 PLCG2 PRPF31 SCYL3 SIK1B SUV39H1 TBC1D1 TBC1D22B ZBTB24
Entrez ID		55633	431707
HPRD ID		15475	17275
Ensembl ID		ENSG00000065491	ENSG00000162624
Uniprot IDs		Q9NU19	Q68G74
PDB IDs		6D0S
Enriched GO Terms of Interacting Partners?
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