TBC1D22B and TEPSIN

Data Source:
BioGRID (two hybrid)

		TBC1D22B	TEPSIN
Description		TBC1 domain family member 22B	TEPSIN adaptor related protein complex 4 accessory protein
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GO Annotations	Cellular Component		Cytoplasm Golgi Apparatus Cytosol Nuclear Speck AP-4 Adaptor Complex Coated Vesicle Membrane Extrinsic Component Of Organelle Membrane Nuclear Membrane Trans-Golgi Network Membrane
	Molecular Function	GTPase Activator Activity Protein Binding 14-3-3 Protein Binding	Protein Binding
	Biological Process	Intracellular Protein Transport Activation Of GTPase Activity Regulation Of Cilium Assembly
Pathways
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Blood glucose levels ( 31928498) Platelet count ( 27863252) Systolic blood pressure ( 31928498) Triglyceride levels ( 31928498)	IgG N-glycosylation phenotypes (multivariate analysis) ( 32128391)
Interacting Genes		58 interacting genes: AP1B1 ARHGEF9 BLZF1 CALCOCO2 CARD10 CCDC57 CCDC88B CDR2 CEP63 CEP70 COG6 DAPK1 DDIT4L DEUP1 EFHC2 EXOC8 FHL3 FXR1 FXR2 GFAP GOLGA2 HMG20A HOMER3 HOOK2 HSD17B14 IKZF3 KIFC3 KRT34 KRT40 LHX8 LIMS1 LRRK2 MFHAS1 MID2 MTUS2 PICK1 PLEKHG4 PNMA5 RBM10 RBM48 REL SIAH1 SLAIN1 SORBS3 SPATA2 TACC3 TEPSIN TEX11 TP53BP2 TRIM23 TRIM27 TRIM54 TRIP6 VPS52 ZFP90 ZNF438 ZNF76 ZSCAN4	127 interacting genes: AATK ACBD7 AGRN AP1M1 AP4B1 APOL6 APP ASAP3 ASB3 BCL2L14 BCL2L15 BHLHB9 BIRC7 BPIFA1 BTBD3 C1orf109 C1QTNF4 CBX8 CCDC146 CCNC CDC23 CINP CLCNKA CLIC3 CNTF CPNE7 CSNK2A1 CTAG1A CTAG1B CYSRT1 DEF6 DUSP29 DUSP4 DZIP1L EIF1AD FAM214B FAM90A1 FARS2 FKBP6 FLACC1 FNDC3B GNG13 GOLGA2 GPANK1 GRB10 GRIPAP1 GUCD1 HAT1 HCK HPCA HSF2BP HSPB7 IL16 IQGAP1 KCTD6 KCTD9 KHNYN KLHL38 KRT31 KRT34 KRT35 KRTAP6-2 LENG1 LGALS14 LMO3 LSM3 LYG2 MAT2B MED18 MFAP1 MLX MORF4L1 MSGN1 MTUS2 NDOR1 NEK6 NGB NME7 NR2C2AP NTAQ1 NUDT14 NUDT21 OAZ3 OR6B1 PAX9 PCDHB3 PLEKHA2 PSMA6 RAB3IP RAD51D RANBP3 RNF135 SEC14L4 SLU7 SNRNP25 SORBS2 SORBS3 SZT2 TAPBPL TBC1D13 TBC1D22B TCEA2 TCL1A TFAP2D THRSP TRAPPC2 TRAPPC2B TRAPPC6A TRIM23 TRIM45 TRIM50 TRIM54 TRIM68 TSEN15 TSEN2 TSHZ3 TSSK3 UBASH3B UTP23 VPS26C WDR25 YPEL3 ZIC1 ZMYND12 ZNF343 ZNF629 ZRSR2
Entrez ID		55633	146705
HPRD ID		15475	08103
Ensembl ID		ENSG00000065491	ENSG00000167302
Uniprot IDs		Q9NU19	Q96N21
PDB IDs		6D0S	5WF9 5WFB
Enriched GO Terms of Interacting Partners?
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