TBC1D22B and SPATA2

Data Source:
BioGRID (two hybrid)

		TBC1D22B	SPATA2
Description		TBC1 domain family member 22B	spermatogenesis associated 2
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GO Annotations	Cellular Component		Fibrillar Center Nucleoplasm Cytoplasm
	Molecular Function	GTPase Activator Activity Protein Binding 14-3-3 Protein Binding	Protein Binding Signaling Receptor Complex Adaptor Activity Protein-containing Complex Binding Ubiquitin-specific Protease Binding
	Biological Process	Intracellular Protein Transport Activation Of GTPase Activity Regulation Of Cilium Assembly	Spermatogenesis Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of Inflammatory Response Regulation Of Necroptotic Process Necroptotic Process Protein K63-linked Deubiquitination Seminiferous Tubule Development Protein Linear Deubiquitination
Pathways
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Blood glucose levels ( 31928498) Platelet count ( 27863252) Systolic blood pressure ( 31928498) Triglyceride levels ( 31928498)	Coronary artery disease ( 29212778) Gut microbiota (beta diversity) ( 27723756) Psoriasis ( 20953189 25574825 18364390)
Interacting Genes		58 interacting genes: AP1B1 ARHGEF9 BLZF1 CALCOCO2 CARD10 CCDC57 CCDC88B CDR2 CEP63 CEP70 COG6 DAPK1 DDIT4L DEUP1 EFHC2 EXOC8 FHL3 FXR1 FXR2 GFAP GOLGA2 HMG20A HOMER3 HOOK2 HSD17B14 IKZF3 KIFC3 KRT34 KRT40 LHX8 LIMS1 LRRK2 MFHAS1 MID2 MTUS2 PICK1 PLEKHG4 PNMA5 RBM10 RBM48 REL SIAH1 SLAIN1 SORBS3 SPATA2 TACC3 TEPSIN TEX11 TP53BP2 TRIM23 TRIM27 TRIM54 TRIP6 VPS52 ZFP90 ZNF438 ZNF76 ZSCAN4	22 interacting genes: ANKRD11 APP ATP6V1H C2CD6 CCDC102B CEP72 DUT EFHC1 GOLGA2 GPANK1 KAT5 KIFC3 LENG1 MAD1L1 OTULIN PTPN6 RNF31 TBC1D22B TNIP1 TRAF2 TRIM27 ZNF835
Entrez ID		55633	9825
HPRD ID		15475	09636
Ensembl ID		ENSG00000065491	ENSG00000158480
Uniprot IDs		Q9NU19	A8K0S9 B4DID4 Q9UM82
PDB IDs		6D0S	5LJM 5LJN
Enriched GO Terms of Interacting Partners?
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