HSD17B11 and CSGALNACT2

Data Source:
BioGRID (two hybrid)

		HSD17B11	CSGALNACT2
Description		hydroxysteroid 17-beta dehydrogenase 11	chondroitin sulfate N-acetylgalactosaminyltransferase 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Lipid Droplet Cytosol	Golgi Membrane Membrane Integral Component Of Golgi Membrane Golgi Cisterna Membrane
	Molecular Function	Estradiol 17-beta-dehydrogenase Activity Protein Binding Steroid Dehydrogenase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor	Protein Binding Acetylgalactosaminyltransferase Activity Metal Ion Binding Glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase Activity Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase Activity
	Biological Process	Estrogen Biosynthetic Process Androgen Catabolic Process	Proteoglycan Biosynthetic Process Chondroitin Sulfate Biosynthetic Process Chondroitin Sulfate Proteoglycan Biosynthetic Process Dermatan Sulfate Proteoglycan Biosynthetic Process Dermatan Sulfate Proteoglycan Biosynthetic Process, Polysaccharide Chain Biosynthetic Process Chondroitin Sulfate Proteoglycan Biosynthetic Process, Polysaccharide Chain Biosynthetic Process
Pathways		Estrogen biosynthesis	Chondroitin sulfate biosynthesis
Drugs		Aetiocholanolone
Diseases
GWAS		Appendicular lean mass ( 28724990) Bulimia nervosa ( 23568457) Lean body mass ( 28724990)	Blood protein levels ( 30072576 29875488) Central corneal thickness ( 32528159) Hirschsprung disease ( 25310821) Multiple sclerosis ( 24076602)
Interacting Genes		59 interacting genes: ADIPOQ AGPAT3 AGPAT4 ANKRD46 BNIP1 CMTM3 CSGALNACT2 CYBC1 DGAT2L6 DHRSX EHHADH ERG28 FAM241B GIMAP1 GOLT1A HTATIP2 LNPEP LRCH4 MS4A1 NEU1 ORMDL1 OTULINL PLP2 PRAF2 PTPN9 RASGRP3 RMDN2 RTP2 SEC22A SEC22B SERPINE1 SFRP4 SFT2D2 SFXN3 SLC22A18 SLC25A46 SLC30A8 STRIT1 STX5 STX7 SYS1 TMEM120B TMEM128 TMEM14B TMEM167B TMEM203 TMEM242 TMEM42 TMEM65 TMX2 TPRG1 TTPA TVP23B UBC UNC50 VAPA VEZT YIF1A YIPF6	20 interacting genes: ARL13B ATP1B4 BSND CLDN2 CREB3L1 CYB5R3 FCGR2A GPR152 HSD17B11 LMNA MFSD14B MUC1 RETREG3 SLC35E3 SSMEM1 SYNE4 SYT1 TMEM143 TMEM52B UBE2I
Entrez ID		51170	55454
HPRD ID		10881	11348
Ensembl ID		ENSG00000198189	ENSG00000169826
Uniprot IDs		Q8NBQ5	A0A0S2Z5F5 A0A0S2Z5F9 A0A0S2Z5K4 Q8N6G5
PDB IDs		1YB1
Enriched GO Terms of Interacting Partners?
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