HSD17B11 and DHRSX

Data Source:
BioGRID (two hybrid)

		HSD17B11	DHRSX
Description		hydroxysteroid 17-beta dehydrogenase 11	dehydrogenase/reductase X-linked
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Lipid Droplet Cytosol	Extracellular Region
	Molecular Function	Estradiol 17-beta-dehydrogenase Activity Protein Binding Steroid Dehydrogenase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor	Protein Binding Oxidoreductase Activity
	Biological Process	Estrogen Biosynthetic Process Androgen Catabolic Process	Positive Regulation Of Autophagy
Pathways		Estrogen biosynthesis
Drugs		Aetiocholanolone
Diseases
GWAS		Appendicular lean mass ( 28724990) Bulimia nervosa ( 23568457) Lean body mass ( 28724990)
Interacting Genes		59 interacting genes: ADIPOQ AGPAT3 AGPAT4 ANKRD46 BNIP1 CMTM3 CSGALNACT2 CYBC1 DGAT2L6 DHRSX EHHADH ERG28 FAM241B GIMAP1 GOLT1A HTATIP2 LNPEP LRCH4 MS4A1 NEU1 ORMDL1 OTULINL PLP2 PRAF2 PTPN9 RASGRP3 RMDN2 RTP2 SEC22A SEC22B SERPINE1 SFRP4 SFT2D2 SFXN3 SLC22A18 SLC25A46 SLC30A8 STRIT1 STX5 STX7 SYS1 TMEM120B TMEM128 TMEM14B TMEM167B TMEM203 TMEM242 TMEM42 TMEM65 TMX2 TPRG1 TTPA TVP23B UBC UNC50 VAPA VEZT YIF1A YIPF6	20 interacting genes: APOC1 APP AQP6 ASPH ATXN1 CIDEB CMTM5 FADS3 GCNT3 HSD17B11 PGRMC2 PIGP RETREG3 RUSF1 TLCD4 TMEM143 TMEM14B TMEM31 TMEM86B ZDHHC15
Entrez ID		51170	207063
HPRD ID		10881	16803
Ensembl ID		ENSG00000198189	ENSG00000169084
Uniprot IDs		Q8NBQ5	Q8N5I4
PDB IDs		1YB1
Enriched GO Terms of Interacting Partners?
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