HSD17B11 and TMEM65

Data Source:
BioGRID (two hybrid)

		HSD17B11	TMEM65
Description		hydroxysteroid 17-beta dehydrogenase 11	transmembrane protein 65
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Lipid Droplet Cytosol	Mitochondrial Inner Membrane Plasma Membrane Intercalated Disc Integral Component Of Membrane
	Molecular Function	Estradiol 17-beta-dehydrogenase Activity Protein Binding Steroid Dehydrogenase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor	Protein Binding
	Biological Process	Estrogen Biosynthetic Process Androgen Catabolic Process	Cardiac Ventricle Development Regulation Of Cardiac Conduction
Pathways		Estrogen biosynthesis
Drugs		Aetiocholanolone
Diseases
GWAS		Appendicular lean mass ( 28724990) Bulimia nervosa ( 23568457) Lean body mass ( 28724990)	Fear of minor pain ( 28701861)
Interacting Genes		59 interacting genes: ADIPOQ AGPAT3 AGPAT4 ANKRD46 BNIP1 CMTM3 CSGALNACT2 CYBC1 DGAT2L6 DHRSX EHHADH ERG28 FAM241B GIMAP1 GOLT1A HTATIP2 LNPEP LRCH4 MS4A1 NEU1 ORMDL1 OTULINL PLP2 PRAF2 PTPN9 RASGRP3 RMDN2 RTP2 SEC22A SEC22B SERPINE1 SFRP4 SFT2D2 SFXN3 SLC22A18 SLC25A46 SLC30A8 STRIT1 STX5 STX7 SYS1 TMEM120B TMEM128 TMEM14B TMEM167B TMEM203 TMEM242 TMEM42 TMEM65 TMX2 TPRG1 TTPA TVP23B UBC UNC50 VAPA VEZT YIF1A YIPF6	33 interacting genes: ABHD16A AQP6 ARL13B CYB561 CYBRD1 EBP ERGIC3 FAM174A FAM209A GJA8 GPR42 HSD17B11 IGSF9 IL3RA JAGN1 JPH1 LMNA MSMO1 PDZK1IP1 PTGES PVR REEP4 RETREG3 SCN3B SLC10A6 SLC18A1 SLC35C2 SLC7A8 TIMMDC1 TMEM101 TMEM80 TMX2 ZFYVE27
Entrez ID		51170	157378
HPRD ID		10881	14102
Ensembl ID		ENSG00000198189	ENSG00000164983
Uniprot IDs		Q8NBQ5	Q6PI78
PDB IDs		1YB1
Enriched GO Terms of Interacting Partners?
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