HSD17B11 and UNC50

Data Source:
BioGRID (two hybrid)

		HSD17B11	UNC50
Description		hydroxysteroid 17-beta dehydrogenase 11	unc-50 inner nuclear membrane RNA binding protein
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Lipid Droplet Cytosol	Nuclear Inner Membrane Integral Component Of Golgi Membrane
	Molecular Function	Estradiol 17-beta-dehydrogenase Activity Protein Binding Steroid Dehydrogenase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor	RNA Binding Protein Binding
	Biological Process	Estrogen Biosynthetic Process Androgen Catabolic Process	Transport Protein Transport
Pathways		Estrogen biosynthesis
Drugs		Aetiocholanolone
Diseases
GWAS		Appendicular lean mass ( 28724990) Bulimia nervosa ( 23568457) Lean body mass ( 28724990)	Diverticular disease ( 30177863)
Interacting Genes		59 interacting genes: ADIPOQ AGPAT3 AGPAT4 ANKRD46 BNIP1 CMTM3 CSGALNACT2 CYBC1 DGAT2L6 DHRSX EHHADH ERG28 FAM241B GIMAP1 GOLT1A HTATIP2 LNPEP LRCH4 MS4A1 NEU1 ORMDL1 OTULINL PLP2 PRAF2 PTPN9 RASGRP3 RMDN2 RTP2 SEC22A SEC22B SERPINE1 SFRP4 SFT2D2 SFXN3 SLC22A18 SLC25A46 SLC30A8 STRIT1 STX5 STX7 SYS1 TMEM120B TMEM128 TMEM14B TMEM167B TMEM203 TMEM242 TMEM42 TMEM65 TMX2 TPRG1 TTPA TVP23B UBC UNC50 VAPA VEZT YIF1A YIPF6	33 interacting genes: AQP6 CLEC10A CLRN1 CREB3 DARS2 EBP ELOVL4 ERGIC3 FAM209A FCER1G FFAR2 FITM2 GPR152 GPX8 HSD17B11 HSD17B13 IFNGR2 KCNJ6 LMNA MFF MFSD14B MGST3 MTIF3 MUC1 REEP4 SAR1A SGPL1 SLC10A1 SLC10A6 TMED8 TMEM14B TMEM167B TMEM234
Entrez ID		51170	25972
HPRD ID		10881	18259
Ensembl ID		ENSG00000198189	ENSG00000115446
Uniprot IDs		Q8NBQ5	A0A0S2Z612 J3KQ47 Q53HI1
PDB IDs		1YB1
Enriched GO Terms of Interacting Partners?
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