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ARSA and CETN2
Data Source:
BioGRID
(two hybrid)
ARSA
CETN2
Description
arylsulfatase A
centrin 2
Image
GO Annotations
Cellular Component
Extracellular Region
Lysosome
Endoplasmic Reticulum Lumen
Azurophil Granule Lumen
Lysosomal Lumen
Extracellular Exosome
Nucleoplasm
Centrosome
Centriole
Cytosol
Photoreceptor Connecting Cilium
Ciliary Basal Body
Nuclear Pore Nuclear Basket
Apical Part Of Cell
Transcription Export Complex 2
XPC Complex
9+2 Motile Cilium
Molecular Function
Arylsulfatase Activity
Cerebroside-sulfatase Activity
Calcium Ion Binding
Protein Binding
Sulfuric Ester Hydrolase Activity
Calcium Ion Binding
Protein Binding
Microtubule Binding
G-protein Beta/gamma-subunit Complex Binding
Heterotrimeric G-protein Binding
Biological Process
Glycosphingolipid Metabolic Process
Neutrophil Degranulation
G2/M Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
Nucleotide-excision Repair, DNA Damage Recognition
Nucleotide-excision Repair, DNA Duplex Unwinding
Nucleotide-excision Repair
Nucleotide-excision Repair, Preincision Complex Assembly
Centriole Replication
Spermatogenesis
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Protein Transport
Regulation Of Cytokinesis
MRNA Transport
Cell Division
Global Genome Nucleotide-excision Repair
Ciliary Basal Body-plasma Membrane Docking
Pathways
Glycosphingolipid metabolism
The activation of arylsulfatases
Neutrophil degranulation
Regulation of PLK1 Activity at G2/M Transition
SUMOylation of DNA damage response and repair proteins
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
DNA Damage Recognition in GG-NER
Formation of Incision Complex in GG-NER
AURKA Activation by TPX2
Drugs
4-Nitrocatechol sulfate
2-Amino-3-Hydroxy-3-Phosphonooxy-Propionic Acid
Diseases
Metachromatic leukodystrophy (MLD)
GWAS
Blood metabolite levels (
24816252
)
Fibrinogen (
23969696
)
Fibrinogen levels (
28107422
)
QT interval (ambient particulate matter interaction) (
28749367
)
Urinary metabolite levels in chronic kidney disease (
31959995
)
vWF and FVIII levels (
30586737
)
Interacting Genes
18 interacting genes:
ANXA11
BMPR2
CAMK2B
CCDC22
CETN2
CLEC4G
CTSL
EID2B
FOXI1
GAL3ST1
PKN1
POU1F1
PPIC
PROP1
RHOXF2
SNCA
TRIP13
VENTX
8 interacting genes:
ARSA
CCP110
PNMA5
POC5
PRMT6
SFI1
SGSM1
XPC
Entrez ID
410
1069
HPRD ID
09617
02051
Ensembl ID
ENSG00000100299
ENSG00000147400
Uniprot IDs
A0A0C4DFZ2
B4DVI5
P15289
P41208
PDB IDs
1AUK
1E1Z
1E2S
1E33
1E3C
1N2K
1N2L
2AIJ
2AIK
2HI8
1M39
1ZMZ
2A4J
2GGM
2K2I
2OBH
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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