CETN2 and POC5

Data Source:
BioGRID (two hybrid, two hybrid)

		CETN2	POC5
Description		centrin 2	POC5 centriolar protein
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Centrosome Centriole Cytosol Photoreceptor Connecting Cilium Ciliary Basal Body Nuclear Pore Nuclear Basket Apical Part Of Cell Transcription Export Complex 2 XPC Complex 9+2 Motile Cilium	Nucleoplasm Centrosome Centriole Cytosol
	Molecular Function	Calcium Ion Binding Protein Binding Microtubule Binding G-protein Beta/gamma-subunit Complex Binding Heterotrimeric G-protein Binding	Protein Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Nucleotide-excision Repair, DNA Damage Recognition Nucleotide-excision Repair, DNA Duplex Unwinding Nucleotide-excision Repair Nucleotide-excision Repair, Preincision Complex Assembly Centriole Replication Spermatogenesis Regulation Of G2/M Transition Of Mitotic Cell Cycle Protein Transport Regulation Of Cytokinesis MRNA Transport Cell Division Global Genome Nucleotide-excision Repair Ciliary Basal Body-plasma Membrane Docking	Cell Cycle
Pathways		Regulation of PLK1 Activity at G2/M Transition SUMOylation of DNA damage response and repair proteins Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane DNA Damage Recognition in GG-NER Formation of Incision Complex in GG-NER AURKA Activation by TPX2
Drugs
Diseases
GWAS			Adult body size ( 32376654) Body mass index ( 28552196 26961502 28892062 29615537 25673413 29273807 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Body size at age 10 ( 32376654) Diastolic blood pressure ( 28135244 27841878 30578418) Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644) HDL cholesterol ( 30275531) HDL cholesterol levels ( 32203549) Metabolic syndrome ( 31589552) Pulse pressure ( 30578418) Total cholesterol levels ( 29615537) Type 2 diabetes ( 30054458 30297969 29632382) Type 2 diabetes (adjusted for BMI) ( 29632382) Weight ( 28552196)
Interacting Genes		8 interacting genes: ARSA CCP110 PNMA5 POC5 PRMT6 SFI1 SGSM1 XPC	7 interacting genes: CALM1 CALM2 CALM3 CETN1 CETN2 CETN3 FAM161A
Entrez ID		1069	134359
HPRD ID		02051	08188
Ensembl ID		ENSG00000147400	ENSG00000152359
Uniprot IDs		P41208	Q8NA72
PDB IDs		1M39 1ZMZ 2A4J 2GGM 2K2I 2OBH
Enriched GO Terms of Interacting Partners?
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