ARSA and PPIC

Data Source:
BioGRID (two hybrid)

		ARSA	PPIC
Description		arylsulfatase A	peptidylprolyl isomerase C
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GO Annotations	Cellular Component	Extracellular Region Lysosome Endoplasmic Reticulum Lumen Azurophil Granule Lumen Lysosomal Lumen Extracellular Exosome	Cytoplasm Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	Arylsulfatase Activity Cerebroside-sulfatase Activity Calcium Ion Binding Protein Binding Sulfuric Ester Hydrolase Activity	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Cyclosporin A Binding
	Biological Process	Glycosphingolipid Metabolic Process Neutrophil Degranulation	Protein Peptidyl-prolyl Isomerization Protein Folding
Pathways		Glycosphingolipid metabolism The activation of arylsulfatases Neutrophil degranulation
Drugs		4-Nitrocatechol sulfate 2-Amino-3-Hydroxy-3-Phosphonooxy-Propionic Acid	Proline
Diseases		Metachromatic leukodystrophy (MLD)
GWAS		Blood metabolite levels ( 24816252) Fibrinogen ( 23969696) Fibrinogen levels ( 28107422) QT interval (ambient particulate matter interaction) ( 28749367) Urinary metabolite levels in chronic kidney disease ( 31959995) vWF and FVIII levels ( 30586737)	Aortic root size ( 19584346) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Diverticular disease ( 30177863) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		18 interacting genes: ANXA11 BMPR2 CAMK2B CCDC22 CETN2 CLEC4G CTSL EID2B FOXI1 GAL3ST1 PKN1 POU1F1 PPIC PROP1 RHOXF2 SNCA TRIP13 VENTX	13 interacting genes: ARSA BANP CAPNS2 FAM25A FAM25C FAM25G LGALS3BP SGTA SGTB UBAP1 UBQLN1 UBQLN2 UBQLN4
Entrez ID		410	5480
HPRD ID		09617	00459
Ensembl ID		ENSG00000100299	ENSG00000168938
Uniprot IDs		A0A0C4DFZ2 B4DVI5 P15289	P45877
PDB IDs		1AUK 1E1Z 1E2S 1E33 1E3C 1N2K 1N2L 2AIJ 2AIK 2HI8	2ESL
Enriched GO Terms of Interacting Partners?
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