TM4SF1 and DNAJA1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TM4SF1	DNAJA1
Description		transmembrane 4 L six family member 1	DnaJ heat shock protein family (Hsp40) member A1
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Plasma Membrane Integral Component Of Membrane	Nucleus Mitochondrion Cytosol Microtubule Cytoskeleton Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome Cytoplasmic Side Of Endoplasmic Reticulum Membrane
	Molecular Function	Molecular_function Protein Binding	G Protein-coupled Receptor Binding ATPase Activator Activity Protein Binding ATP Binding Hsp70 Protein Binding Tat Protein Binding Ubiquitin Protein Ligase Binding Metal Ion Binding Low-density Lipoprotein Particle Receptor Binding Unfolded Protein Binding Chaperone Binding C3HC4-type RING Finger Domain Binding
	Biological Process	Biological_process	Protein Folding Response To Unfolded Protein Spermatogenesis Response To Heat Flagellated Sperm Motility Androgen Receptor Signaling Pathway Negative Regulation Of Protein Ubiquitination Positive Regulation Of ATPase Activity DNA Damage Response, Detection Of DNA Damage Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of JUN Kinase Activity Regulation Of Protein Transport Protein Localization To Mitochondrion Toxin Transport Negative Regulation Of Establishment Of Protein Localization To Mitochondrion Negative Regulation Of Nitrosative Stress-induced Intrinsic Apoptotic Signaling Pathway
Pathways			HSP90 chaperone cycle for steroid hormone receptors (SHR)
Drugs
Diseases
GWAS		Ischemic stroke (large artery atherosclerosis) ( 29531354)
Interacting Genes		7 interacting genes: ANPEP DDR1 DNAJA1 HSPA8 SDCBP2 SLC13A1 TUBA4A	24 interacting genes: ARL4D BCS1L BRCA1 CAV2 CD58 CDC16 CFTR ERG FZR1 HIVEP1 HMGCL HSPA8 LINC01554 LSM2 NELFCD NUDT3 PAXIP1 PGR PTEN PTTG1 SUMO2 SUMO4 TM4SF1 TXN
Entrez ID		4071	3301
HPRD ID		01854	04159
Ensembl ID		ENSG00000169908	ENSG00000086061
Uniprot IDs		P30408	B7Z5C0 P31689
PDB IDs			2LO1 2M6Y 6E8M
Enriched GO Terms of Interacting Partners?
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