PRPH and PRPH2

Data Source:
HPRD (in vivo, in vitro)

		PRPH	PRPH2
Description		peripherin	peripherin 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Intermediate Filament Membrane Axon Perikaryon Type III Intermediate Filament Extracellular Exosome	Photoreceptor Outer Segment Photoreceptor Inner Segment Integral Component Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Structural Molecule Activity Protein Binding	Protein Binding Protein Homodimerization Activity
	Biological Process	Intermediate Filament Cytoskeleton Organization	Cell Adhesion Visual Perception Photoreceptor Cell Outer Segment Organization Detection Of Light Stimulus Involved In Visual Perception Protein Homooligomerization Protein Heterooligomerization Retina Development In Camera-type Eye
Pathways
Drugs
Diseases		Amyotrophic lateral sclerosis (ALS); Lou Gehrig's disease	Vitelliform macular dystrophy, including: Best disease / Juvenile vitelliform macular dystrophy (VMD2) ; Adult-onset vitelliform macular dystrophy (AVMD) Retinitis pigmentosa (RP) Macular degeneration, including: Age-related macular degeneration (ARMD); Patterned dystrophy of retinal pigment epithelium (PDREP); Retinal macular dystrophy 2 (MCDR2); X-linked atrophic macular degeneration (MDXLA)
GWAS		Prostate cancer ( 21743467) Sural nerve amplitude potential ( 30992453)	Pulse pressure ( 27841878)
Interacting Genes		36 interacting genes: CDC37 CT55 DDX6 DES FCHO1 INCA1 KIFC3 KRT14 KRT15 KRT16 KRT19 KRT20 KRT24 KRT27 KRT31 KRT75 LCA5L LENG1 LMNB1 LNX1 MAGOHB MYO5A NXF1 PIAS2 PPP1R13B PPP1R18 PRKAA2 PRPH2 PSMA1 TCEA2 TCP10L TTC23 VIM ZC4H2 ZMAT2 ZNF572	4 interacting genes: CNGB1 GRAP2 PRPH ROM1
Entrez ID		5630	5961
HPRD ID		01365	01553
Ensembl ID		ENSG00000135406	ENSG00000112619
Uniprot IDs		B3KWQ6 P41219	P23942
PDB IDs
Enriched GO Terms of Interacting Partners?
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