PRPH and KRT19

Data Source:
BioGRID (two hybrid)

		PRPH	KRT19
Description		peripherin	keratin 19
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Intermediate Filament Membrane Axon Perikaryon Type III Intermediate Filament Extracellular Exosome	Cytosol Intermediate Filament Plasma Membrane Dystrophin-associated Glycoprotein Complex Apicolateral Plasma Membrane Z Disc Sarcolemma Costamere Extracellular Exosome Cell Periphery Terminal Web
	Molecular Function	Structural Molecule Activity Protein Binding	Structural Constituent Of Cytoskeleton Protein Binding Structural Constituent Of Muscle Protein-containing Complex Binding
	Biological Process	Intermediate Filament Cytoskeleton Organization	Notch Signaling Pathway Viral Process Keratinization Response To Estrogen Sarcomere Organization Cell Differentiation Involved In Embryonic Placenta Development Cornification
Pathways			Keratinization Formation of the cornified envelope
Drugs
Diseases		Amyotrophic lateral sclerosis (ALS); Lou Gehrig's disease
GWAS		Prostate cancer ( 21743467) Sural nerve amplitude potential ( 30992453)
Interacting Genes		36 interacting genes: CDC37 CT55 DDX6 DES FCHO1 INCA1 KIFC3 KRT14 KRT15 KRT16 KRT19 KRT20 KRT24 KRT27 KRT31 KRT75 LCA5L LENG1 LMNB1 LNX1 MAGOHB MYO5A NXF1 PIAS2 PPP1R13B PPP1R18 PRKAA2 PRPH2 PSMA1 TCEA2 TCP10L TTC23 VIM ZC4H2 ZMAT2 ZNF572	79 interacting genes: ABI2 AMOT AMOTL2 APC ARL4A BEX2 C1orf109 CARD9 CCDC146 CCHCR1 CEP57L1 COPS4 DEPP1 DGCR6L DMD EIF4E2 EIF4ENIF1 ESR1 EXOC8 FAM107A FAM124B FANCG GFAP GLYCTK HAUS1 HGS IKZF3 KDM1A KIFC3 KRT1 KRT15 KRT2 KRT3 KRT4 KRT5 KRT6A KRT6B KRT6C KRT71 KRT72 KRT74 KRT75 KRT77 KRT78 KRT79 KRT8 KRT80 KRT81 KRT83 KRT85 KRT86 LENG1 LGALS14 NFKBID PCDHB12 PCM1 PKN1 PLEKHA5 PNN POLL POLR1C PPP1R18 PRPH PSMA1 RCOR3 SFI1 SGF29 SMARCB1 SMARCE1 SNAPIN SPG21 TBC1D7 TCHP TFPT TUBG1 UBE2I UCHL5 USHBP1 ZNF638
Entrez ID		5630	3880
HPRD ID		01365	01007
Ensembl ID		ENSG00000135406	ENSG00000171345
Uniprot IDs		B3KWQ6 P41219	P08727
PDB IDs
Enriched GO Terms of Interacting Partners?
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