Description |
growth factor receptor bound protein 14 |
tripartite motif containing 27 |
Image |
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No pdb structure |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
- Adventurousness ( 30643258)
- Blood pressure ( 24954895 21572416)
- Body fat percentage ( 26833246 31453325)
- Body fat percentage variance ( 31453325)
- Body mass index ( 29381148 26426971)
- Body mass index (age>50) ( 26426971)
- Body mass index x sex x age interaction (4df test) ( 26426971)
- Coronary artery disease ( 32469254 33020668)
- Diastolic blood pressure ( 28739976 27618452)
- Diastolic blood pressure (cigarette smoking interaction) ( 29455858)
- Diastolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
- Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
- Fasting blood insulin ( 25631608)
- Fasting blood insulin (BMI interaction) ( 22581228)
- Glomerular filtration rate in chronic kidney disease ( 26420894)
- Glycine levels ( 30837465)
- HDL cholesterol levels ( 30698716)
- HDL cholesterol levels in current drinkers ( 30698716)
- HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
- HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
- Hip circumference ( 25673412)
- Hip circumference adjusted for BMI ( 25673412)
- Hypertension ( 30487518)
- Immunoglobulin A vasculitis ( 28698626)
- LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
- Mean arterial pressure ( 29403010 30487518)
- Mean arterial pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
- Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962)
- Number of sexual partners ( 30643258)
- Perceived sweetness of sucrose ( 31005972)
- Pulse pressure ( 27841878 28739976 30487518)
- Pulse pressure x alcohol consumption interaction (2df test) ( 29912962)
- Response to statin therapy ( 20339536)
- Sexual dimorphism in anthropometric traits ( 23754948)
- Systolic blood pressure ( 26390057 28135244 27841878 29403010 28739976 27618447 27618452)
- Systolic blood pressure (cigarette smoking interaction) ( 29455858)
- Systolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
- Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
- Triglyceride levels ( 32203549 30698716)
- Triglyceride levels in current drinkers ( 30698716)
- Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
- Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
- Type 2 diabetes ( 22885922 24509480 21874001 30297969 29632382 32499647 30718926 28869590)
- Type 2 diabetes (adjusted for BMI) ( 29632382)
- Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
- Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500)
- Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
- Waist circumference adjusted for BMI in active individuals ( 28448500)
- Waist circumference adjusted for BMI in non-smokers ( 28443625)
- Waist circumference adjusted for body mass index ( 25673412 28448500)
- Waist-hip ratio ( 25673412 20935629)
- Waist-to-hip ratio adjusted for BMI ( 26426971)
- Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
- Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971)
- Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
- Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500)
- Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
- Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500)
- Waist-to-hip ratio adjusted for BMI in inactive individuals ( 28448500)
- Waist-to-hip ratio adjusted for BMI in non-smokers ( 28443625)
- Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
- Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500)
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Interacting Genes |
25 interacting genes:
CDC5L
CHFR
DAPK3
EGFR
ERBB2
FGFR1
FRS3
GIGYF1
GIGYF2
GOLGA2
HCK
IGF1R
INSR
IRS1
MAP3K14
MET
PDGFRA
PDGFRB
PRKCZ
SQSTM1
STK26
TEK
TNKS2
TRIM27
TRIM55
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354 interacting genes:
ABCA1
ABCF3
ABHD17A
ACSF3
AEN
AMMECR1
AMOTL2
AP1M1
ARHGEF3
ARHGEF5
ARID5A
ARIH2
ARMC7
ARNT2
ARPIN
ATPAF2
ATXN7
AXIN1
BABAM1
BAG1
BAG3
BAG5
BEGAIN
BEX2
BMI1
BMP7
BYSL
C1orf109
CAPN7
CARD10
CATSPER1
CBX8
CCDC102B
CCDC185
CCDC187
CCDC198
CCDC87
CCDC92
CCHCR1
CDC20B
CDC23
CDC7
CDK18
CDKL3
CFAP206
CHCHD3
CHD4
CHUK
CKS1B
CLK2
CNNM3
COX5B
CPNE2
CPNE7
CREB5
CSRP2
CWF19L2
DBF4B
DCX
DDX6
DGCR6
DMRT3
DNMT1
DTNB
DTNBP1
EHHADH
EID1
EIF3D
EIF3E
EIF4A3
EIF4E
EIF4E2
ENKD1
EPC1
ERCC3
EXOC8
FAM110A
FAM126A
FAM126B
FAM161A
FAM193B
FAM214A
FAM214B
FAM83A
FAM90A1
FANCM
FARS2
FASTKD5
FBF1
FBXL19
FBXW5
FHL3
FNDC11
FOXB1
FOXC2
FXYD6
GADD45GIP1
GAS2L2
GATAD2B
GCC2-AS1
GEM
GFAP
GFI1B
GFM2
GLYCTK
GNE
GNPDA2
GPANK1
GPKOW
GRB14
GRB2
GSE1
GTF2F1
HAPLN2
HAUS1
HCK
HDAC1
HDAC4
HGS
HIP1R
HNRNPLL
HOXB5
HOXB9
HOXC8
HR
IGFN1
IKBKB
IKBKE
IL16
ILF2
ILK
INO80B
INPP5J
IP6K3
IQCE
IQCN
IQUB
JOSD1
KANSL1
KAT14
KAT5
KCTD15
KCTD9
KIF1A
KIF9
KIFC3
KRT3
KRT75
KRT76
LAGE3
LASP1
LENG1
LGALS14
LINC00526
LINGO1
LMNB2
LMO1
LMO4
LNX1
LONRF1
MAD2L2
MAGEA11
MAGED4B
MAGEF1
MAGOHB
MAPKBP1
MAT2B
MBD4
MCM7
MCOLN1
MDM2
MED21
MEMO1
MIA3
MID2
MOS
MRPL40
MSRB1
MTMR6
MVP
MYO15B
NCK2
NCOA1
NDE1
NDEL1
NEBL
NEDD9
NEIL2
NEK6
NELFE
NIF3L1
NME7
NOTCH2NLA
NR1D2
NTAQ1
NUDT21
OAS1
OTUB2
P2RX7
PIAS1
PIAS2
PIAS3
PIAS4
PIBF1
PIMREG
PIN1
PKN1
PLEKHN1
PML
POLE2
POLR1C
POLR3C
POM121
PPID
PPL
PPP1R18
PRAM1
PRKAA1
PRPF18
PRPF31
PRR35
PSMA1
PSMB1
PSMB3
PTPMT1
PTPN23
PUS7L
QARS1
RAB29
RAMAC
RB1
RBM23
RBM41
RBX1
RCOR3
REL
RHPN1
RIBC1
RIN1
RNF213
RNF25
RNF6
RSPH14
RXRB
SCNM1
SDCBP
SH2D4A
SIAH1
SIRPA
SLC15A3
SMARCB1
SMARCD1
SMG9
SNRPA
SNRPB2
SORBS3
SPATA2
SPATC1L
SRSF2
STAMBPL1
STK16
STK25
STK26
SYNGAP1
SYT17
SYT6
TACO1
TBC1D22B
TBK1
TCEA2
TCEANC
TCHP
TEAD4
TEX33
THOC1
TLE5
TMSB4X
TMSB4XP6
TNS4
TP53
TPM3
TPRKB
TRAF4
TRAF5
TRIM11
TRIM21
TRIM23
TRIM29
TRIM31
TRIM32
TRIM42
TRIM43
TRIM50
TRIM55
TRIM9
TSGA10IP
TSHZ3
TTLL10
TUBGCP4
TUFT1
TXNDC9
UBASH3A
UBE2A
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E2
UBE2E3
UBE2H
UBE2I
UBE2J1
UBE2K
UBE2L6
UBE2N
UBE2O
UBE2T
UBE2U
UBE2W
UBE2Z
UBL5
UCHL3
UCHL5
UHRF2
USE1
USP2
UTP14C
UTP23
VEZF1
VPS25
VPS28
VPS9D1
WT1-AS
XPA
YJU2
ZBTB16
ZC2HC1C
ZFC3H1
ZFHX3
ZFYVE21
ZGPAT
ZMYND19
ZNF250
ZNF384
ZNF414
ZNF417
ZNF446
ZNF572
ZNF580
ZNF581
ZNF587
ZNF688
ZNF79
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Entrez ID |
2888 |
5987 |
HPRD ID |
03313 |
15996 |
Ensembl ID |
ENSG00000115290
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ENSG00000204713
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Uniprot IDs |
Q14449
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A0A1U9X8R9
P14373
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PDB IDs |
2AUG
2AUH
4K81
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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