IFIT5 and LONP1

Data Source:
BioGRID (two hybrid)

		IFIT5	LONP1
Description		interferon induced protein with tetratricopeptide repeats 5	lon peptidase 1, mitochondrial
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GO Annotations	Cellular Component	Cytosol Plasma Membrane IkappaB Kinase Complex Actin Cytoskeleton Ruffle Membrane Apical Part Of Cell	Nucleoplasm Mitochondrion Mitochondrial Matrix Cytosol Membrane Mitochondrial Nucleoid
	Molecular Function	TRNA Binding RNA Cap Binding Double-stranded DNA Binding RNA Binding Single-stranded RNA Binding Protein Binding Poly(U) RNA Binding	Mitochondrial Promoter Sequence-specific DNA Binding Single-stranded DNA Binding Single-stranded RNA Binding ATP-dependent Peptidase Activity Serine-type Endopeptidase Activity Protein Binding ATP Binding ATPase Activity Identical Protein Binding ADP Binding Sequence-specific DNA Binding G-quadruplex DNA Binding DNA Polymerase Binding
	Biological Process	Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Viral Genome Replication Innate Immune Response Defense Response To Virus	Mitochondrial Genome Maintenance Response To Hypoxia Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Mitochondrion Organization Aging Response To Hormone Response To Aluminum Ion Mitochondrial DNA Metabolic Process Cellular Response To Oxidative Stress Chaperone-mediated Protein Complex Assembly Proteolysis Involved In Cellular Protein Catabolic Process Oxidation-dependent Protein Catabolic Process
Pathways		Interferon alpha/beta signaling
Drugs
Diseases
GWAS			Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494) Red cell distribution width ( 32888494)
Interacting Genes		17 interacting genes: A2M APOE CDC37 CHUK ECSIT IFIT1 IFIT3 IKBKG LONP1 MAST1 PRDX2 PSEN2 RAD23A RNF32 SARAF SRPK1 SRPK2	11 interacting genes: A2M APOE CDC37 CDC42 CYP2C8 ECSIT IFIT3 IFIT5 LOXL4 MAST1 RNF32
Entrez ID		24138	9361
HPRD ID		17130	05689
Ensembl ID		ENSG00000152778	ENSG00000196365
Uniprot IDs		Q13325	P36776
PDB IDs		3ZGQ 4HOQ 4HOR 4HOS 4HOT 4J0U	2X36
Enriched GO Terms of Interacting Partners?
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