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FCER1G and TMEM218
Data Source:
BioGRID
(two hybrid)
FCER1G
TMEM218
Description
Fc fragment of IgE receptor Ig
transmembrane protein 218
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
External Side Of Plasma Membrane
Cell Surface
Fc-epsilon Receptor I Complex
Tertiary Granule Membrane
Ficolin-1-rich Granule Membrane
Cilium
Integral Component Of Membrane
Molecular Function
Protein Binding
IgE Receptor Activity
IgE Binding
IgG Binding
Identical Protein Binding
Protein Binding
Biological Process
Stimulatory C-type Lectin Receptor Signaling Pathway
Neutrophil Activation Involved In Immune Response
T Cell Differentiation Involved In Immune Response
Fc Receptor Mediated Stimulatory Signaling Pathway
Blood Coagulation
Regulation Of Platelet Activation
Immunoglobulin Mediated Immune Response
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Platelet Activation
Neutrophil Chemotaxis
Receptor Internalization
Positive Regulation Of Interleukin-4 Production
Fc-gamma Receptor Signaling Pathway
Fc-epsilon Receptor Signaling Pathway
Interleukin-3-mediated Signaling Pathway
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I
Defense Response To Bacterium
Neutrophil Degranulation
Innate Immune Response
Positive Regulation Of Phagocytosis
Leukocyte Migration
Cellular Response To Low-density Lipoprotein Particle Stimulus
Pathways
GPVI-mediated activation cascade
Cell surface interactions at the vascular wall
Fc epsilon receptor (FCERI) signaling
Fc epsilon receptor (FCERI) signaling
Role of LAT2/NTAL/LAB on calcium mobilization
Role of LAT2/NTAL/LAB on calcium mobilization
FCERI mediated MAPK activation
FCERI mediated Ca+2 mobilization
FCERI mediated Ca+2 mobilization
FCERI mediated NF-kB activation
Dectin-2 family
Dectin-2 family
Neutrophil degranulation
Platelet Adhesion to exposed collagen
Drugs
Benzylpenicilloyl polylysine
Diseases
GWAS
Aggressive periodontitis (
28449029
)
Allergic disease (asthma, hay fever or eczema) (
29083406
)
Allergic rhinitis (
30013184
31361310
)
Allergy (
27182965
)
Asthma (
31361310
30929738
32296059
31619474
)
Asthma (childhood onset) (
30929738
)
Asthma onset (childhood vs adult) (
30929738
)
Mean platelet volume (
32888494
27863252
)
Neutrophil count (
32888494
)
Platelet count (
32888494
)
Platelet distribution width (
32888494
27863252
)
White blood cell count (
32888494
)
Breast cancer (survival) (
25890600
)
Familial lung adenocarcinoma (
29924316
)
Interacting Genes
83 interacting genes:
ADGRE2
C2CD2L
CDIPT
CERS4
CLCA4
CLEC4E
CNIH1
COX20
CYP4F2
DEFB127
DGAT2L6
EBP
FA2H
FAM209A
FAXDC2
FCER1A
FCGR3A
FFAR2
FUNDC2
FXYD6
GIMAP5
GJA5
GP6
GPR61
IER3IP1
KCNA1
KCNN3
KIR2DL4
LEPROTL1
LMNA
LNPEP
LYN
MFF
MGLL
NCR1
NCR3
NRM
ORMDL2
PDZK1IP1
PEMT
PEX16
PLCG2
PLP2
RUSF1
SEC22B
SFXN1
SFXN3
SLC10A1
SLC13A4
SLC18A1
SLC1A1
SLC30A8
SLC35G2
SLC38A7
SLC39A2
SLC39A9
SLC7A1
SLC7A14
SMIM1
STX12
SYK
SYNJ2BP
SYS1
THBD
TMEM107
TMEM120B
TMEM140
TMEM14B
TMEM179B
TMEM19
TMEM218
TMEM31
TPRG1
TSPO
TSPO2
UBE2J1
UBIAD1
UNC50
UNC93A
VAMP1
YIF1A
YIPF4
YIPF6
72 interacting genes:
APH1A
AQP2
AQP6
ARL13B
ASZ1
ATP6V0E1
BSCL2
CD300A
CD53
CD79A
CLDN2
CLEC10A
CLEC17A
CPLX4
CREB3L1
CTLA4
DAGLA
EBP
ELOVL2
ELOVL4
EMP1
ERGIC3
FAM209A
FCER1G
FRMD3
GDAP1
GJB1
GJB4
GJB6
GPR152
GPR61
GPX8
IFNGR2
KCNJ6
KCNK5
KIR2DL3
LDLRAD1
LHFPL5
LMNA
LSMEM2
MFF
MS4A3
MTIF3
NPFFR2
PCNA
PDCD1LG2
PIK3IP1
PLEKHO1
PSCA
RETREG3
SAR1A
SDC3
SLC10A4
SLC10A6
SLC18A1
SMIM3
SSMEM1
TM4SF18
TMED8
TMEM106C
TMEM182
TMEM207
TMEM234
TMEM31
TMEM45B
TMEM52B
TMEM88
TMPRSS2
TRHR
TSPAN12
TSPAN18
VSIR
Entrez ID
2207
219854
HPRD ID
00916
19054
Ensembl ID
ENSG00000158869
ENSG00000150433
Uniprot IDs
P30273
A2RU14
PDB IDs
Enriched GO Terms of Interacting Partners
?
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