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FCER1G and SEC22B
Data Source:
BioGRID
(two hybrid)
FCER1G
SEC22B
Description
Fc fragment of IgE receptor Ig
SEC22 homolog B, vesicle trafficking protein
Image
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
External Side Of Plasma Membrane
Cell Surface
Fc-epsilon Receptor I Complex
Tertiary Granule Membrane
Ficolin-1-rich Granule Membrane
Golgi Membrane
Endoplasmic Reticulum Membrane
Endoplasmic Reticulum-Golgi Intermediate Compartment
Synaptic Vesicle
ER To Golgi Transport Vesicle Membrane
Integral Component Of Membrane
Transport Vesicle
COPI-coated Vesicle
Phagocytic Vesicle Membrane
SNARE Complex
Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
Melanosome
Molecular Function
Protein Binding
IgE Receptor Activity
IgE Binding
IgG Binding
Identical Protein Binding
SNAP Receptor Activity
Protein Binding
Syntaxin Binding
Biological Process
Stimulatory C-type Lectin Receptor Signaling Pathway
Neutrophil Activation Involved In Immune Response
T Cell Differentiation Involved In Immune Response
Fc Receptor Mediated Stimulatory Signaling Pathway
Blood Coagulation
Regulation Of Platelet Activation
Immunoglobulin Mediated Immune Response
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Platelet Activation
Neutrophil Chemotaxis
Receptor Internalization
Positive Regulation Of Interleukin-4 Production
Fc-gamma Receptor Signaling Pathway
Fc-epsilon Receptor Signaling Pathway
Interleukin-3-mediated Signaling Pathway
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I
Defense Response To Bacterium
Neutrophil Degranulation
Innate Immune Response
Positive Regulation Of Phagocytosis
Leukocyte Migration
Cellular Response To Low-density Lipoprotein Particle Stimulus
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum
Protein Transport
Positive Regulation Of Protein Catabolic Process
COPII Vesicle Coating
Vesicle Fusion With Golgi Apparatus
Negative Regulation Of Autophagosome Assembly
Vesicle Fusion With Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Membrane
Pathways
GPVI-mediated activation cascade
Cell surface interactions at the vascular wall
Fc epsilon receptor (FCERI) signaling
Fc epsilon receptor (FCERI) signaling
Role of LAT2/NTAL/LAB on calcium mobilization
Role of LAT2/NTAL/LAB on calcium mobilization
FCERI mediated MAPK activation
FCERI mediated Ca+2 mobilization
FCERI mediated Ca+2 mobilization
FCERI mediated NF-kB activation
Dectin-2 family
Dectin-2 family
Neutrophil degranulation
Platelet Adhesion to exposed collagen
ER-Phagosome pathway
COPII-mediated vesicle transport
Cargo concentration in the ER
COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Benzylpenicilloyl polylysine
Diseases
GWAS
Aggressive periodontitis (
28449029
)
Allergic disease (asthma, hay fever or eczema) (
29083406
)
Allergic rhinitis (
30013184
31361310
)
Allergy (
27182965
)
Asthma (
31361310
30929738
32296059
31619474
)
Asthma (childhood onset) (
30929738
)
Asthma onset (childhood vs adult) (
30929738
)
Mean platelet volume (
32888494
27863252
)
Neutrophil count (
32888494
)
Platelet count (
32888494
)
Platelet distribution width (
32888494
27863252
)
White blood cell count (
32888494
)
Iris color (L* coordinate) (
30895295
)
Interacting Genes
83 interacting genes:
ADGRE2
C2CD2L
CDIPT
CERS4
CLCA4
CLEC4E
CNIH1
COX20
CYP4F2
DEFB127
DGAT2L6
EBP
FA2H
FAM209A
FAXDC2
FCER1A
FCGR3A
FFAR2
FUNDC2
FXYD6
GIMAP5
GJA5
GP6
GPR61
IER3IP1
KCNA1
KCNN3
KIR2DL4
LEPROTL1
LMNA
LNPEP
LYN
MFF
MGLL
NCR1
NCR3
NRM
ORMDL2
PDZK1IP1
PEMT
PEX16
PLCG2
PLP2
RUSF1
SEC22B
SFXN1
SFXN3
SLC10A1
SLC13A4
SLC18A1
SLC1A1
SLC30A8
SLC35G2
SLC38A7
SLC39A2
SLC39A9
SLC7A1
SLC7A14
SMIM1
STX12
SYK
SYNJ2BP
SYS1
THBD
TMEM107
TMEM120B
TMEM140
TMEM14B
TMEM179B
TMEM19
TMEM218
TMEM31
TPRG1
TSPO
TSPO2
UBE2J1
UBIAD1
UNC50
UNC93A
VAMP1
YIF1A
YIPF4
YIPF6
56 interacting genes:
ABHD16A
AIG1
AQP6
B3GAT3
CD79A
CERS6
CLDN7
CLRN1
CPLX4
CREB3
CREB3L1
DPM3
EBP
ELOVL4
ERGIC3
FAM174A
FAM209A
FCER1G
FNDC9
GJA8
GJB5
GJB6
GORAB
GPR152
GPX8
HIBADH
HSD17B11
HSD17B13
IFNGR2
JAGN1
KIR2DL3
LHFPL1
LHFPL5
LMNA
MFF
MFSD5
MGST2
MGST3
MMGT1
MRPS18B
NDUFAF2
REEP4
RELL2
RHBDD1
SERINC2
SLC35C2
STX1A
STX2
STX4
STX5
TLCD4
TM4SF19
TMEM139
TMEM167B
TMEM229B
TMEM86B
Entrez ID
2207
9554
HPRD ID
00916
04939
Ensembl ID
ENSG00000158869
ENSG00000265808
Uniprot IDs
P30273
O75396
PDB IDs
2NUP
2NUT
3EGD
3EGX
Enriched GO Terms of Interacting Partners
?
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Tagcloud (Difference)
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Tagcloud (Intersection)
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