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TMEM218 and PDCD1LG2
Data Source:
BioGRID
(two hybrid)
TMEM218
PDCD1LG2
Description
transmembrane protein 218
programmed cell death 1 ligand 2
Image
No pdb structure
GO Annotations
Cellular Component
Cilium
Integral Component Of Membrane
Extracellular Region
Plasma Membrane
External Side Of Plasma Membrane
Endomembrane System
Integral Component Of Membrane
Molecular Function
Protein Binding
Molecular_function
Protein Binding
Biological Process
Adaptive Immune Response
Immune Response
Cell Surface Receptor Signaling Pathway
T Cell Costimulation
Negative Regulation Of Interferon-gamma Production
Negative Regulation Of Interleukin-10 Production
Positive Regulation Of T Cell Proliferation
Negative Regulation Of T Cell Proliferation
Negative Regulation Of Activated T Cell Proliferation
Cellular Response To Lipopolysaccharide
Pathways
PD-1 signaling
Drugs
Diseases
GWAS
Breast cancer (survival) (
25890600
)
Familial lung adenocarcinoma (
29924316
)
Blood protein levels (
30072576
29875488
28240269
)
Interacting Genes
72 interacting genes:
APH1A
AQP2
AQP6
ARL13B
ASZ1
ATP6V0E1
BSCL2
CD300A
CD53
CD79A
CLDN2
CLEC10A
CLEC17A
CPLX4
CREB3L1
CTLA4
DAGLA
EBP
ELOVL2
ELOVL4
EMP1
ERGIC3
FAM209A
FCER1G
FRMD3
GDAP1
GJB1
GJB4
GJB6
GPR152
GPR61
GPX8
IFNGR2
KCNJ6
KCNK5
KIR2DL3
LDLRAD1
LHFPL5
LMNA
LSMEM2
MFF
MS4A3
MTIF3
NPFFR2
PCNA
PDCD1LG2
PIK3IP1
PLEKHO1
PSCA
RETREG3
SAR1A
SDC3
SLC10A4
SLC10A6
SLC18A1
SMIM3
SSMEM1
TM4SF18
TMED8
TMEM106C
TMEM182
TMEM207
TMEM234
TMEM31
TMEM45B
TMEM52B
TMEM88
TMPRSS2
TRHR
TSPAN12
TSPAN18
VSIR
20 interacting genes:
ATP6V0C
ERMP1
GALNT15
GPR37L1
KTN1
LRP10
MFSD6
PDCD1
RUSF1
SLC35C2
SLC38A1
SLC38A7
SLC41A2
SLC7A1
SMIM3
TAS2R10
TMEM147
TMEM218
TMEM239
TMEM97
Entrez ID
219854
80380
HPRD ID
19054
16147
Ensembl ID
ENSG00000150433
ENSG00000197646
Uniprot IDs
A2RU14
Q9BQ51
PDB IDs
6UMT
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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