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FCER1G and FAM209A
Data Source:
BioGRID
(two hybrid)
FCER1G
FAM209A
Description
Fc fragment of IgE receptor Ig
family with sequence similarity 209 member A
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
External Side Of Plasma Membrane
Cell Surface
Fc-epsilon Receptor I Complex
Tertiary Granule Membrane
Ficolin-1-rich Granule Membrane
Nucleus
Integral Component Of Membrane
Extracellular Exosome
Molecular Function
Protein Binding
IgE Receptor Activity
IgE Binding
IgG Binding
Identical Protein Binding
Molecular_function
Protein Binding
Biological Process
Stimulatory C-type Lectin Receptor Signaling Pathway
Neutrophil Activation Involved In Immune Response
T Cell Differentiation Involved In Immune Response
Fc Receptor Mediated Stimulatory Signaling Pathway
Blood Coagulation
Regulation Of Platelet Activation
Immunoglobulin Mediated Immune Response
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Platelet Activation
Neutrophil Chemotaxis
Receptor Internalization
Positive Regulation Of Interleukin-4 Production
Fc-gamma Receptor Signaling Pathway
Fc-epsilon Receptor Signaling Pathway
Interleukin-3-mediated Signaling Pathway
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I
Defense Response To Bacterium
Neutrophil Degranulation
Innate Immune Response
Positive Regulation Of Phagocytosis
Leukocyte Migration
Cellular Response To Low-density Lipoprotein Particle Stimulus
Biological_process
Pathways
GPVI-mediated activation cascade
Cell surface interactions at the vascular wall
Fc epsilon receptor (FCERI) signaling
Fc epsilon receptor (FCERI) signaling
Role of LAT2/NTAL/LAB on calcium mobilization
Role of LAT2/NTAL/LAB on calcium mobilization
FCERI mediated MAPK activation
FCERI mediated Ca+2 mobilization
FCERI mediated Ca+2 mobilization
FCERI mediated NF-kB activation
Dectin-2 family
Dectin-2 family
Neutrophil degranulation
Platelet Adhesion to exposed collagen
Drugs
Benzylpenicilloyl polylysine
Diseases
GWAS
Aggressive periodontitis (
28449029
)
Allergic disease (asthma, hay fever or eczema) (
29083406
)
Allergic rhinitis (
30013184
31361310
)
Allergy (
27182965
)
Asthma (
31361310
30929738
32296059
31619474
)
Asthma (childhood onset) (
30929738
)
Asthma onset (childhood vs adult) (
30929738
)
Mean platelet volume (
32888494
27863252
)
Neutrophil count (
32888494
)
Platelet count (
32888494
)
Platelet distribution width (
32888494
27863252
)
White blood cell count (
32888494
)
Heschl's gyrus morphology (
25130324
)
Interacting Genes
83 interacting genes:
ADGRE2
C2CD2L
CDIPT
CERS4
CLCA4
CLEC4E
CNIH1
COX20
CYP4F2
DEFB127
DGAT2L6
EBP
FA2H
FAM209A
FAXDC2
FCER1A
FCGR3A
FFAR2
FUNDC2
FXYD6
GIMAP5
GJA5
GP6
GPR61
IER3IP1
KCNA1
KCNN3
KIR2DL4
LEPROTL1
LMNA
LNPEP
LYN
MFF
MGLL
NCR1
NCR3
NRM
ORMDL2
PDZK1IP1
PEMT
PEX16
PLCG2
PLP2
RUSF1
SEC22B
SFXN1
SFXN3
SLC10A1
SLC13A4
SLC18A1
SLC1A1
SLC30A8
SLC35G2
SLC38A7
SLC39A2
SLC39A9
SLC7A1
SLC7A14
SMIM1
STX12
SYK
SYNJ2BP
SYS1
THBD
TMEM107
TMEM120B
TMEM140
TMEM14B
TMEM179B
TMEM19
TMEM218
TMEM31
TPRG1
TSPO
TSPO2
UBE2J1
UBIAD1
UNC50
UNC93A
VAMP1
YIF1A
YIPF4
YIPF6
231 interacting genes:
-
ADGRE2
ADIPOQ
AGTRAP
AIG1
ALG8
ANKRD46
APMAP
APOC3
APOD
APOL2
AQP1
AQP2
AQP3
ARV1
ASGR1
ATP13A1
B4GALNT2
BDNF
BET1
BIK
BMP10
BNIP2
BNIP3
BTN2A2
C11orf24
C14orf180
C1GALT1
C2
C3orf52
C4orf3
CANT1
CCL4L2
CD53
CD59
CD81
CDIPT
CDS1
CDS2
CLCA4
CLDN19
CLDN2
CLDN4
CLDND2
CLEC4G
CLN6
CMTM7
CNIH1
CNPY3
COL4A5
COL8A2
COMT
CTRL
CTSA
CTXN3
CXCL16
CYB561D2
CYB5B
CYBC1
DEFB121
DEFB128
DNAJC30
DOLK
EBP
EMC6
EMD
ENTPD3
EOGT
ERG28
ERMP1
FA2H
FAM20B
FAM3C
FATE1
FCER1G
FDFT1
FIS1
FXYD3
GAST
GET3
GHITM
GIMAP1
GJB2
GKN1
GKN2
GOSR2
GPR108
GPR151
GPR37L1
GYPA
HACD2
HHATL
HMOX1
HMOX2
HTATIP2
IGFBP5
INSIG2
JAGN1
KIR2DL3
LHFPL5
LPAR3
LRP10
MAL
MARCHF2
MFF
MGLL
MIP
MMD
MMD2
MS4A1
MS4A13
MYADM
MYADML2
NAPB
NAT8
NCR3
NINJ2
NRM
NXPE3
OLFM4
ORMDL3
OTOR
PAQR7
PEDS1-UBE2V1
PGAP2
PGLYRP3
PLN
PLP1
PLP2
PLPP4
PLPP6
PMP22
PNLIPRP1
PRB1
PTCH1
RHAG
RPRM
RTP2
RUSF1
S100A2
SCARF1
SCGB1D1
SCRG1
SEC22A
SEC22B
SEC61G
SELENOK
SEMA6C
SERP1
SFTPC
SLC13A3
SLC1A1
SLC30A8
SLC35A1
SLC35A4
SLC35B4
SLC35E3
SLC35G2
SLC38A7
SLC52A2
SLC7A14
SMCO4
SMIM1
SNORC
STATH
STX1B
STX3
STX5
STX8
SYNGR1
SYT15
TECR
TEX264
TFRC
THBD
THSD7B
TM6SF2
TMBIM6
TMEM100
TMEM107
TMEM11
TMEM120A
TMEM128
TMEM140
TMEM141
TMEM14B
TMEM14C
TMEM203
TMEM208
TMEM218
TMEM222
TMEM229B
TMEM236
TMEM243
TMEM254
TMEM42
TMEM43
TMEM47
TMEM50B
TMEM60
TMEM65
TMEM72
TMEM79
TMEM86A
TMEM86B
TMEM97
TMPRSS4
TMUB2
TNF
TNFRSF10C
TNMD
TRAF3IP3
TRAM1L1
TSPAN2
TSPAN33
TSPAN7
TSPO
TWSG1
UBE2J1
UBIAD1
UNC50
UPK1B
VAMP3
VAMP4
VAMP5
VKORC1
VMP1
WFDC2
WFS1
YIPF6
ZFPL1
Entrez ID
2207
200232
HPRD ID
00916
18536
Ensembl ID
ENSG00000158869
ENSG00000124103
Uniprot IDs
P30273
Q5JX71
PDB IDs
Enriched GO Terms of Interacting Partners
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