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COL4A5 and THAP4
Data Source:
BioGRID
(two hybrid)
COL4A5
THAP4
Description
collagen type IV alpha 5 chain
THAP domain containing 4
Image
GO Annotations
Cellular Component
Extracellular Region
Collagen Type IV Trimer
Basement Membrane
Extracellular Space
Endoplasmic Reticulum Lumen
Extracellular Matrix
Neuromuscular Junction
Collagen-containing Extracellular Matrix
Cellular_component
Molecular Function
Extracellular Matrix Structural Constituent
Extracellular Matrix Structural Constituent Conferring Tensile Strength
DNA Binding
Protein Binding
Heme Binding
Identical Protein Binding
Metal Ion Binding
Peroxynitrite Isomerase Activity
Nitric Oxide Binding
Biological Process
Neuromuscular Junction Development
Extracellular Matrix Organization
Collagen-activated Tyrosine Kinase Receptor Signaling Pathway
Tyrosine Metabolic Process
Nitrate Metabolic Process
Pathways
Collagen degradation
Collagen degradation
Extracellular matrix organization
Collagen biosynthesis and modifying enzymes
Signaling by PDGF
Assembly of collagen fibrils and other multimeric structures
Integrin cell surface interactions
Integrin cell surface interactions
Anchoring fibril formation
Crosslinking of collagen fibrils
Laminin interactions
Laminin interactions
Non-integrin membrane-ECM interactions
ECM proteoglycans
NCAM1 interactions
Collagen chain trimerization
Regulation of expression of SLITs and ROBOs
Drugs
Diseases
Alport syndrome
GWAS
Brain structure (
20171287
)
Platelet count (
32888494
)
Prostate cancer (
23535732
)
Thyroid stimulating hormone levels (
32769997
)
Interacting Genes
46 interacting genes:
ABHD4
ANTXR2
ANXA7
APP
ATP6V0B
BSND
CD53
CD79A
CD93
CDKN1A
CERS4
CLDN7
DAZAP2
DCN
ELOVL4
ERGIC3
FAM209A
FBLN2
FFAR2
FN1
GPX8
HABP2
KCNJ6
MATN2
MFF
MMP9
MTIF3
NCR3LG1
NEMP1
NR1H2
OSM
RELL2
RNF10
SAR1A
SERPINE2
SLC10A4
SLC10A6
SLC16A2
SLC18A1
SLC35C2
SLC39A2
SMN1
THAP4
TK1
TMEM80
TSPO2
42 interacting genes:
AGTRAP
AIG1
AMD1
ANKRD46
APP
BSND
CACNG1
CD81
CLCA4
CMTM5
CMTM7
COL4A5
CPNE2
CTSA
CYP4F2
DGAT2L6
FKBP7
GIMAP1
GPR37L1
IGFBP5
LAT
LPAR3
MAL2
MAPK6
MOB4
MS4A1
NDRG4
PLP2
RMDN2
RTP2
SCAMP1
SLC30A8
SYP
TMEM107
TMEM60
TMEM86A
TMEM86B
TNFRSF10D
TPD52
TRIM54
TTPA
YIPF6
Entrez ID
1287
51078
HPRD ID
02363
11630
Ensembl ID
ENSG00000188153
ENSG00000176946
Uniprot IDs
A7MBN3
P29400
Q49AM6
Q8WY91
PDB IDs
5NAZ
3IA8
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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