THAP4 and CACNG1

Data Source:
BioGRID (two hybrid)

		THAP4	CACNG1
Description		THAP domain containing 4	calcium voltage-gated channel auxiliary subunit gamma 1
Image			No pdb structure
GO Annotations	Cellular Component	Cellular_component	Plasma Membrane Integral Component Of Plasma Membrane T-tubule Sarcolemma L-type Voltage-gated Calcium Channel Complex
	Molecular Function	DNA Binding Protein Binding Heme Binding Identical Protein Binding Metal Ion Binding Peroxynitrite Isomerase Activity Nitric Oxide Binding	Voltage-gated Calcium Channel Activity Calcium Channel Regulator Activity Protein Binding
	Biological Process	Tyrosine Metabolic Process Nitrate Metabolic Process	Cardiac Conduction Sarcoplasmic Reticulum Calcium Ion Transport Calcium Ion Transmembrane Transport Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel
Pathways
Drugs			Ergocalciferol Enflurane Ibutilide Diltiazem Spironolactone Lercanidipine Ethanol Fluspirilene Butamben Bioallethrin
Diseases
GWAS		Brain structure ( 20171287) Platelet count ( 32888494) Prostate cancer ( 23535732) Thyroid stimulating hormone levels ( 32769997)	Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		42 interacting genes: AGTRAP AIG1 AMD1 ANKRD46 APP BSND CACNG1 CD81 CLCA4 CMTM5 CMTM7 COL4A5 CPNE2 CTSA CYP4F2 DGAT2L6 FKBP7 GIMAP1 GPR37L1 IGFBP5 LAT LPAR3 MAL2 MAPK6 MOB4 MS4A1 NDRG4 PLP2 RMDN2 RTP2 SCAMP1 SLC30A8 SYP TMEM107 TMEM60 TMEM86A TMEM86B TNFRSF10D TPD52 TRIM54 TTPA YIPF6	13 interacting genes: CPLX4 FFAR2 GAD2 GPX8 HSD17B13 LMNA MGST3 MUC1 ODF4 THAP4 TLCD4 TMEM45B VAPA
Entrez ID		51078	786
HPRD ID		11630	00249
Ensembl ID		ENSG00000176946	ENSG00000108878
Uniprot IDs		Q8WY91	Q06432
PDB IDs		3IA8
Enriched GO Terms of Interacting Partners?
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