COL4A5 and BSND

Data Source:
BioGRID (two hybrid)

		COL4A5	BSND
Description		collagen type IV alpha 5 chain	barttin CLCNK type accessory subunit beta
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Type IV Trimer Basement Membrane Extracellular Space Endoplasmic Reticulum Lumen Extracellular Matrix Neuromuscular Junction Collagen-containing Extracellular Matrix	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Basolateral Plasma Membrane Protein-containing Complex
	Molecular Function	Extracellular Matrix Structural Constituent Extracellular Matrix Structural Constituent Conferring Tensile Strength	Chloride Channel Activity Protein Binding Chloride Channel Regulator Activity
	Biological Process	Neuromuscular Junction Development Extracellular Matrix Organization Collagen-activated Tyrosine Kinase Receptor Signaling Pathway	Chloride Transport Ion Transmembrane Transport Chloride Transmembrane Transport
Pathways		Collagen degradation Collagen degradation Extracellular matrix organization Collagen biosynthesis and modifying enzymes Signaling by PDGF Assembly of collagen fibrils and other multimeric structures Integrin cell surface interactions Integrin cell surface interactions Anchoring fibril formation Crosslinking of collagen fibrils Laminin interactions Laminin interactions Non-integrin membrane-ECM interactions ECM proteoglycans NCAM1 interactions Collagen chain trimerization Regulation of expression of SLITs and ROBOs	Stimuli-sensing channels
Drugs
Diseases		Alport syndrome	Bartter syndrome
GWAS			Allergic rhinitis ( 25085501) Carotid intima media thickness x smoking interaction ( 32117412) Coronary artery disease ( 32469254 33020668) Medication use (HMG CoA reductase inhibitors) ( 31015401) Mitochondrial DNA copy number ( 30704525)
Interacting Genes		46 interacting genes: ABHD4 ANTXR2 ANXA7 APP ATP6V0B BSND CD53 CD79A CD93 CDKN1A CERS4 CLDN7 DAZAP2 DCN ELOVL4 ERGIC3 FAM209A FBLN2 FFAR2 FN1 GPX8 HABP2 KCNJ6 MATN2 MFF MMP9 MTIF3 NCR3LG1 NEMP1 NR1H2 OSM RELL2 RNF10 SAR1A SERPINE2 SLC10A4 SLC10A6 SLC16A2 SLC18A1 SLC35C2 SLC39A2 SMN1 THAP4 TK1 TMEM80 TSPO2	28 interacting genes: ADIPOQ APOL2 APP ARFIP1 BMP10 CDIPT CERT1 COL4A5 COL8A2 CSGALNACT2 CTSA ECPAS FATE1 GAD2 IGFBP5 JAGN1 MYG1 PBX3 PLSCR2 PTPN9 SLC30A8 SPG21 STX8 TBRG4 THAP4 TMEM60 VAMP3 ZFPL1
Entrez ID		1287	7809
HPRD ID		02363	05914
Ensembl ID		ENSG00000188153	ENSG00000162399
Uniprot IDs		A7MBN3 P29400 Q49AM6	Q5VU50 Q8WZ55
PDB IDs		5NAZ
Enriched GO Terms of Interacting Partners?
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